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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRM6 All Species: 21.52
Human Site: Y475 Identified Species: 47.33
UniProt: O15303 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15303 NP_000834.2 877 95468 Y475 G R Y D I F Q Y Q A T N G S A
Chimpanzee Pan troglodytes NP_001158171 879 95564 Y477 G R Y D I F Q Y Q A T N G S A
Rhesus Macaque Macaca mulatta A3QP01 839 95041 Q452 A L H L E I V Q W Q W G L S Q
Dog Lupus familis XP_538573 878 95312 Y476 G R Y D I F Q Y Q A A N G S A
Cat Felis silvestris
Mouse Mus musculus Q5NCH9 871 95175 Y469 G R Y D I F Q Y Q A T N G S A
Rat Rattus norvegicus P35349 871 95071 Y469 G R Y D I F Q Y Q A T N G S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520992 875 96315 F471 G R Y D I F Q F Q L T N S S A
Chicken Gallus gallus XP_425426 924 103611 Y476 G R Y D I F Q Y Q I T N K S T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5U9X3 867 97118 W454 L G Y D L F L W E G D Q S D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91685 976 108467 V492 Y N N Y L L N V S F I D L A G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09630 999 113258 K568 K P K S M D K K R R M T D D E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 26.9 94.6 N.A. 93.1 93 N.A. 79.2 66.4 N.A. 25.3 N.A. 42.1 N.A. 35.4 N.A.
Protein Similarity: 100 99.1 45.2 95.9 N.A. 95.7 95.6 N.A. 88.1 78.3 N.A. 45.8 N.A. 58 N.A. 53.3 N.A.
P-Site Identity: 100 100 6.6 93.3 N.A. 100 100 N.A. 80 80 N.A. 20 N.A. 0 N.A. 0 N.A.
P-Site Similarity: 100 100 13.3 93.3 N.A. 100 100 N.A. 86.6 80 N.A. 40 N.A. 20 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 46 10 0 0 10 55 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 73 0 10 0 0 0 0 10 10 10 19 0 % D
% Glu: 0 0 0 0 10 0 0 0 10 0 0 0 0 0 19 % E
% Phe: 0 0 0 0 0 73 0 10 0 10 0 0 0 0 0 % F
% Gly: 64 10 0 0 0 0 0 0 0 10 0 10 46 0 10 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 64 10 0 0 0 10 10 0 0 0 0 % I
% Lys: 10 0 10 0 0 0 10 10 0 0 0 0 10 0 0 % K
% Leu: 10 10 0 10 19 10 10 0 0 10 0 0 19 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 10 10 0 0 0 10 0 0 0 0 64 0 0 0 % N
% Pro: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 64 10 64 10 0 10 0 0 10 % Q
% Arg: 0 64 0 0 0 0 0 0 10 10 0 0 0 0 0 % R
% Ser: 0 0 0 10 0 0 0 0 10 0 0 0 19 73 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 55 10 0 0 10 % T
% Val: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 10 10 0 10 0 0 0 0 % W
% Tyr: 10 0 73 10 0 0 0 55 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _