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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMM2
All Species:
49.7
Human Site:
S230
Identified Species:
72.89
UniProt:
O15305
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15305
NP_000294.1
246
28082
S230
D
P
R
T
M
G
Y
S
V
T
A
P
E
D
T
Chimpanzee
Pan troglodytes
XP_510805
262
29611
P230
W
G
W
S
S
R
E
P
L
D
V
R
G
I
G
Rhesus Macaque
Macaca mulatta
XP_001102327
246
28005
S230
D
P
R
T
V
G
Y
S
V
T
A
P
E
D
T
Dog
Lupus familis
XP_547133
246
27865
T230
D
P
R
T
V
G
Y
T
V
T
A
P
E
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2M7
242
27638
T226
D
P
R
T
V
G
Y
T
V
T
A
P
E
D
T
Rat
Rattus norvegicus
NP_001100443
242
27690
T226
D
P
R
T
V
G
Y
T
V
T
A
P
E
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506595
230
26152
T214
D
A
R
T
V
G
Y
T
V
T
R
P
E
D
T
Chicken
Gallus gallus
NP_001026639
247
28306
S231
D
S
R
T
K
G
H
S
V
T
S
P
Q
D
T
Frog
Xenopus laevis
NP_001087784
246
28053
S229
D
S
R
T
I
G
H
S
V
T
S
P
E
E
T
Zebra Danio
Brachydanio rerio
NP_956378
250
28394
E233
D
P
R
T
I
G
H
E
V
K
S
P
E
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTZ6
254
29648
R237
D
P
R
T
I
S
H
R
V
Y
T
P
K
D
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XUE6
245
28123
T226
D
E
R
T
V
G
H
T
V
E
G
P
E
D
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002320113
246
27837
T229
S
E
R
T
V
G
H
T
V
T
S
P
D
D
T
Maize
Zea mays
NP_001140792
249
28111
T231
S
E
R
T
V
G
H
T
V
T
S
P
S
D
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O80840
246
27743
S229
S
P
K
T
I
G
H
S
V
T
S
P
D
D
T
Baker's Yeast
Sacchar. cerevisiae
P07283
254
29044
S237
D
E
R
T
I
G
H
S
V
Q
S
P
D
D
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.5
98.3
93.9
N.A.
89.8
91.8
N.A.
80
84.6
76
70.4
N.A.
52.7
N.A.
44.7
N.A.
Protein Similarity:
100
86.2
99.5
97.1
N.A.
94.3
95.1
N.A.
86.9
92.3
90.2
85.5
N.A.
71.2
N.A.
61.3
N.A.
P-Site Identity:
100
0
93.3
86.6
N.A.
86.6
86.6
N.A.
73.3
66.6
66.6
66.6
N.A.
53.3
N.A.
60
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
86.6
86.6
93.3
86.6
N.A.
73.3
N.A.
80
N.A.
Percent
Protein Identity:
58.5
59.8
N.A.
61.7
57.4
N.A.
Protein Similarity:
76
77.5
N.A.
77.6
70.4
N.A.
P-Site Identity:
53.3
53.3
N.A.
60
60
N.A.
P-Site Similarity:
86.6
80
N.A.
93.3
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
0
0
0
32
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
75
0
0
0
0
0
0
0
0
7
0
0
19
88
0
% D
% Glu:
0
25
0
0
0
0
7
7
0
7
0
0
57
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
0
88
0
0
0
0
7
0
7
0
7
% G
% His:
0
0
0
0
0
0
57
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
32
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
0
0
7
0
7
0
0
0
0
7
0
0
7
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
50
0
0
0
0
0
7
0
0
0
94
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% Q
% Arg:
0
0
88
0
0
7
0
7
0
0
7
7
0
0
0
% R
% Ser:
19
13
0
7
7
7
0
38
0
0
44
0
7
0
0
% S
% Thr:
0
0
0
94
0
0
0
44
0
69
7
0
0
0
94
% T
% Val:
0
0
0
0
50
0
0
0
94
0
7
0
0
0
0
% V
% Trp:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
38
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _