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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMM2
All Species:
33.33
Human Site:
Y191
Identified Species:
48.89
UniProt:
O15305
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15305
NP_000294.1
246
28082
Y191
P
D
G
W
D
K
R
Y
C
L
R
H
V
E
N
Chimpanzee
Pan troglodytes
XP_510805
262
29611
Y191
P
D
G
W
D
K
R
Y
C
L
R
H
V
E
N
Rhesus Macaque
Macaca mulatta
XP_001102327
246
28005
Y191
P
D
G
W
D
K
R
Y
C
L
R
H
V
E
N
Dog
Lupus familis
XP_547133
246
27865
Y191
P
D
G
W
D
K
R
Y
C
L
R
H
V
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2M7
242
27638
Y187
P
E
G
W
D
K
R
Y
C
L
R
H
L
E
H
Rat
Rattus norvegicus
NP_001100443
242
27690
Y187
P
D
G
W
D
K
R
Y
C
L
R
H
L
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506595
230
26152
F175
P
D
G
W
D
K
R
F
C
L
G
Q
V
E
N
Chicken
Gallus gallus
NP_001026639
247
28306
Y192
P
D
G
W
D
K
R
Y
C
L
G
I
I
A
E
Frog
Xenopus laevis
NP_001087784
246
28053
F190
P
T
G
W
D
K
T
F
C
L
G
I
L
E
N
Zebra Danio
Brachydanio rerio
NP_956378
250
28394
Y194
P
E
G
W
D
K
R
Y
C
L
G
I
V
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTZ6
254
29648
C198
H
G
W
D
K
T
Y
C
L
R
H
I
E
A
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XUE6
245
28123
T187
F
P
T
G
W
D
K
T
F
C
L
Q
Y
L
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002320113
246
27837
K190
V
F
P
Q
G
W
D
K
T
Y
C
L
R
Y
L
Maize
Zea mays
NP_001140792
249
28111
K192
V
F
P
Q
G
W
D
K
T
Y
C
L
R
Y
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O80840
246
27743
K190
V
F
P
K
G
W
D
K
T
Y
C
L
Q
Y
L
Baker's Yeast
Sacchar. cerevisiae
P07283
254
29044
Y198
P
A
G
W
D
K
T
Y
C
L
Q
H
V
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.5
98.3
93.9
N.A.
89.8
91.8
N.A.
80
84.6
76
70.4
N.A.
52.7
N.A.
44.7
N.A.
Protein Similarity:
100
86.2
99.5
97.1
N.A.
94.3
95.1
N.A.
86.9
92.3
90.2
85.5
N.A.
71.2
N.A.
61.3
N.A.
P-Site Identity:
100
100
100
100
N.A.
80
86.6
N.A.
80
66.6
60
73.3
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
86.6
73.3
73.3
80
N.A.
6.6
N.A.
6.6
N.A.
Percent
Protein Identity:
58.5
59.8
N.A.
61.7
57.4
N.A.
Protein Similarity:
76
77.5
N.A.
77.6
70.4
N.A.
P-Site Identity:
0
0
N.A.
0
73.3
N.A.
P-Site Similarity:
0
0
N.A.
0
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
0
0
0
0
0
0
13
0
% A
% Cys:
0
0
0
0
0
0
0
7
69
7
19
0
0
0
0
% C
% Asp:
0
44
0
7
69
7
19
0
0
0
0
0
0
0
0
% D
% Glu:
0
13
0
0
0
0
0
0
0
0
0
0
7
63
7
% E
% Phe:
7
19
0
0
0
0
0
13
7
0
0
0
0
0
0
% F
% Gly:
0
7
69
7
19
0
0
0
0
0
25
0
0
0
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
7
44
0
0
13
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
25
7
0
0
% I
% Lys:
0
0
0
7
7
69
7
19
0
0
0
0
0
0
13
% K
% Leu:
0
0
0
0
0
0
0
0
7
69
7
19
19
7
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
38
% N
% Pro:
69
7
19
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
13
0
0
0
0
0
0
7
13
7
0
7
% Q
% Arg:
0
0
0
0
0
0
57
0
0
7
38
0
13
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
7
7
0
0
7
13
7
19
0
0
0
0
0
0
% T
% Val:
19
0
0
0
0
0
0
0
0
0
0
0
44
0
7
% V
% Trp:
0
0
7
69
7
19
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
57
0
19
0
0
7
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _