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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMM2
All Species:
32.12
Human Site:
Y201
Identified Species:
47.11
UniProt:
O15305
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15305
NP_000294.1
246
28082
Y201
R
H
V
E
N
D
G
Y
K
T
I
Y
F
F
G
Chimpanzee
Pan troglodytes
XP_510805
262
29611
Y201
R
H
V
E
N
D
G
Y
K
T
I
Y
F
F
G
Rhesus Macaque
Macaca mulatta
XP_001102327
246
28005
Y201
R
H
V
E
N
D
G
Y
K
T
I
Y
F
F
G
Dog
Lupus familis
XP_547133
246
27865
Y201
R
H
V
E
N
D
G
Y
K
T
I
Y
F
F
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2M7
242
27638
Y197
R
H
L
E
H
A
G
Y
K
T
I
Y
F
F
G
Rat
Rattus norvegicus
NP_001100443
242
27690
Y197
R
H
L
E
Q
A
G
Y
K
T
I
Y
F
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506595
230
26152
Y185
G
Q
V
E
N
D
G
Y
K
T
I
Y
F
F
G
Chicken
Gallus gallus
NP_001026639
247
28306
Y202
G
I
I
A
E
D
G
Y
K
T
I
Y
F
F
G
Frog
Xenopus laevis
NP_001087784
246
28053
F200
G
I
L
E
N
E
G
F
S
K
I
Y
F
F
G
Zebra Danio
Brachydanio rerio
NP_956378
250
28394
Y204
G
I
V
E
K
D
S
Y
Q
H
I
H
F
F
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTZ6
254
29648
F208
H
I
E
A
H
Y
K
F
K
E
I
H
F
F
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XUE6
245
28123
F197
L
Q
Y
L
V
P
D
F
D
T
I
H
F
F
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002320113
246
27837
F200
C
L
R
Y
L
D
E
F
S
E
I
H
F
F
G
Maize
Zea mays
NP_001140792
249
28111
F202
C
L
R
Y
L
E
E
F
Q
E
I
H
F
F
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O80840
246
27743
F200
C
L
Q
Y
L
E
D
F
S
E
I
H
F
F
G
Baker's Yeast
Sacchar. cerevisiae
P07283
254
29044
F208
Q
H
V
E
K
D
G
F
K
E
I
H
F
F
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.5
98.3
93.9
N.A.
89.8
91.8
N.A.
80
84.6
76
70.4
N.A.
52.7
N.A.
44.7
N.A.
Protein Similarity:
100
86.2
99.5
97.1
N.A.
94.3
95.1
N.A.
86.9
92.3
90.2
85.5
N.A.
71.2
N.A.
61.3
N.A.
P-Site Identity:
100
100
100
100
N.A.
80
80
N.A.
86.6
66.6
53.3
53.3
N.A.
33.3
N.A.
33.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
86.6
N.A.
86.6
73.3
73.3
66.6
N.A.
53.3
N.A.
46.6
N.A.
Percent
Protein Identity:
58.5
59.8
N.A.
61.7
57.4
N.A.
Protein Similarity:
76
77.5
N.A.
77.6
70.4
N.A.
P-Site Identity:
33.3
26.6
N.A.
26.6
66.6
N.A.
P-Site Similarity:
46.6
53.3
N.A.
46.6
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
13
0
0
0
0
0
0
0
0
0
% A
% Cys:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
57
13
0
7
0
0
0
0
0
0
% D
% Glu:
0
0
7
63
7
19
13
0
0
32
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
44
0
0
0
0
100
100
0
% F
% Gly:
25
0
0
0
0
0
63
0
0
0
0
0
0
0
100
% G
% His:
7
44
0
0
13
0
0
0
0
7
0
44
0
0
0
% H
% Ile:
0
25
7
0
0
0
0
0
0
0
100
0
0
0
0
% I
% Lys:
0
0
0
0
13
0
7
0
63
7
0
0
0
0
0
% K
% Leu:
7
19
19
7
19
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
38
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
13
7
0
7
0
0
0
13
0
0
0
0
0
0
% Q
% Arg:
38
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
7
0
19
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
57
0
0
0
0
0
% T
% Val:
0
0
44
0
7
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
19
0
7
0
57
0
0
0
57
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _