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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMM2
All Species:
31.52
Human Site:
Y64
Identified Species:
46.22
UniProt:
O15305
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15305
NP_000294.1
246
28082
Y64
G
N
D
V
V
E
K
Y
D
Y
V
F
P
E
N
Chimpanzee
Pan troglodytes
XP_510805
262
29611
Y64
G
N
D
V
V
E
K
Y
D
Y
V
F
P
E
N
Rhesus Macaque
Macaca mulatta
XP_001102327
246
28005
Y64
G
N
D
V
V
E
K
Y
D
Y
V
F
P
E
N
Dog
Lupus familis
XP_547133
246
27865
Y64
G
N
D
V
V
K
K
Y
D
Y
V
F
P
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2M7
242
27638
Y60
G
N
D
V
V
E
K
Y
D
Y
V
F
P
E
N
Rat
Rattus norvegicus
NP_001100443
242
27690
Y60
G
N
D
V
V
E
K
Y
D
Y
V
F
P
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506595
230
26152
F48
G
D
D
V
V
G
K
F
D
Y
V
F
P
E
N
Chicken
Gallus gallus
NP_001026639
247
28306
F65
G
D
D
V
V
E
K
F
D
Y
V
F
P
E
N
Frog
Xenopus laevis
NP_001087784
246
28053
F63
G
D
D
V
V
E
Q
F
D
Y
V
F
A
E
N
Zebra Danio
Brachydanio rerio
NP_956378
250
28394
V67
G
D
D
V
I
D
R
V
D
Y
V
F
A
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTZ6
254
29648
F70
G
R
K
I
L
N
E
F
D
F
I
F
P
E
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XUE6
245
28123
F61
F
F
P
V
L
S
L
F
D
Y
T
F
S
E
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002320113
246
27837
Y65
G
K
T
V
I
N
D
Y
D
Y
V
F
S
E
N
Maize
Zea mays
NP_001140792
249
28111
Y67
G
S
T
V
I
T
D
Y
D
Y
V
F
S
E
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O80840
246
27743
Y65
G
K
T
V
T
N
D
Y
D
Y
C
F
S
E
N
Baker's Yeast
Sacchar. cerevisiae
P07283
254
29044
F71
G
P
N
V
L
D
E
F
D
Y
S
F
S
E
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.5
98.3
93.9
N.A.
89.8
91.8
N.A.
80
84.6
76
70.4
N.A.
52.7
N.A.
44.7
N.A.
Protein Similarity:
100
86.2
99.5
97.1
N.A.
94.3
95.1
N.A.
86.9
92.3
90.2
85.5
N.A.
71.2
N.A.
61.3
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
80
86.6
73.3
60
N.A.
40
N.A.
40
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
93.3
86.6
N.A.
80
N.A.
53.3
N.A.
Percent
Protein Identity:
58.5
59.8
N.A.
61.7
57.4
N.A.
Protein Similarity:
76
77.5
N.A.
77.6
70.4
N.A.
P-Site Identity:
60
60
N.A.
53.3
46.6
N.A.
P-Site Similarity:
66.6
73.3
N.A.
53.3
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
25
63
0
0
13
19
0
100
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
44
13
0
0
0
0
0
0
100
0
% E
% Phe:
7
7
0
0
0
0
0
38
0
7
0
100
0
0
0
% F
% Gly:
94
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
19
0
0
0
0
0
7
0
0
0
0
% I
% Lys:
0
13
7
0
0
7
50
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
19
0
7
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
38
7
0
0
19
0
0
0
0
0
0
0
0
100
% N
% Pro:
0
7
7
0
0
0
0
0
0
0
0
0
57
0
0
% P
% Gln:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
0
0
0
7
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
0
0
0
7
0
0
0
0
7
0
32
0
0
% S
% Thr:
0
0
19
0
7
7
0
0
0
0
7
0
0
0
0
% T
% Val:
0
0
0
94
57
0
0
7
0
0
75
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
57
0
94
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _