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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAD51L1 All Species: 15.76
Human Site: Y312 Identified Species: 28.89
UniProt: O15315 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15315 NP_002868.1 384 42196 Y312 N T R L I L Q Y L D S E R R Q
Chimpanzee Pan troglodytes XP_001139007 384 42172 Y312 N T R L I L Q Y L D S E R R Q
Rhesus Macaque Macaca mulatta XP_001108183 384 42265 Y312 N T R L I L Q Y L D S E R R Q
Dog Lupus familis XP_547868 345 38650 Y286 R R L I T S E Y E E T F W H D
Cat Felis silvestris
Mouse Mus musculus O35719 350 38134 C291 E G T S G S S C L V A A L G N
Rat Rattus norvegicus XP_576058 470 51148 Q363 L S L V V S T Q T S C G F S Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P37383 339 36885 A280 V D G A A M F A A D P K K P I
Frog Xenopus laevis Q91918 336 36642 A277 V D G A A M F A A D P K K P I
Zebra Danio Brachydanio rerio NP_998577 373 41204 Y302 N T R L I V Q Y E D S E R R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27297 336 36629 F277 L D G A P G M F D A K K P I G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q9XED7 340 36708 A281 V D G A A M F A G P Q I K P I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SK02 370 40449 K308 I R L V L E A K S G Q R I I K
Baker's Yeast Sacchar. cerevisiae P25453 334 36594 S275 G A S A L F A S A D G R K P I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 96.6 63.7 N.A. 77.5 52.1 N.A. N.A. 26.2 26.2 53.3 N.A. 26.2 N.A. N.A. N.A.
Protein Similarity: 100 99.4 97.6 73.1 N.A. 83.8 63.8 N.A. N.A. 44 42.7 69.5 N.A. 41.4 N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 6.6 6.6 N.A. N.A. 6.6 6.6 86.6 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 33.3 N.A. 13.3 26.6 N.A. N.A. 26.6 26.6 93.3 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 23.9 N.A. 29.4 27.8 N.A.
Protein Similarity: N.A. 42.4 N.A. 51.5 43.2 N.A.
P-Site Identity: N.A. 0 N.A. 0 6.6 N.A.
P-Site Similarity: N.A. 13.3 N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 39 24 0 16 24 24 8 8 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % C
% Asp: 0 31 0 0 0 0 0 0 8 54 0 0 0 0 8 % D
% Glu: 8 0 0 0 0 8 8 0 16 8 0 31 0 0 0 % E
% Phe: 0 0 0 0 0 8 24 8 0 0 0 8 8 0 0 % F
% Gly: 8 8 31 0 8 8 0 0 8 8 8 8 0 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 8 0 0 8 31 0 0 0 0 0 0 8 8 16 31 % I
% Lys: 0 0 0 0 0 0 0 8 0 0 8 24 31 0 8 % K
% Leu: 16 0 24 31 16 24 0 0 31 0 0 0 8 0 0 % L
% Met: 0 0 0 0 0 24 8 0 0 0 0 0 0 0 0 % M
% Asn: 31 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 8 0 0 0 0 8 16 0 8 31 0 % P
% Gln: 0 0 0 0 0 0 31 8 0 0 16 0 0 0 39 % Q
% Arg: 8 16 31 0 0 0 0 0 0 0 0 16 31 31 0 % R
% Ser: 0 8 8 8 0 24 8 8 8 8 31 0 0 8 0 % S
% Thr: 0 31 8 0 8 0 8 0 8 0 8 0 0 0 0 % T
% Val: 24 0 0 16 8 8 0 0 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 39 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _