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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLR3G All Species: 19.09
Human Site: T133 Identified Species: 35
UniProt: O15318 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15318 NP_006458.2 223 25914 T133 A K D A G K G T P L T N T E D
Chimpanzee Pan troglodytes XP_517660 223 25886 T133 A K D A G K G T S L T N T E D
Rhesus Macaque Macaca mulatta XP_001090983 218 25378 L117 W R R L P R E L K I R V R K L
Dog Lupus familis XP_852150 223 25829 T133 A K D T G K G T S L T N T A D
Cat Felis silvestris
Mouse Mus musculus Q6NXY9 223 25929 T134 S K A A A K A T S L I N S A D
Rat Rattus norvegicus NP_001102938 223 26154 T134 A K A T S K G T T L M N S T D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508505 222 26012 T135 A K P S R E V T A L T G T T D
Chicken Gallus gallus XP_424697 216 24895 S132 K P K K A K N S E P K S N L D
Frog Xenopus laevis NP_001089996 216 24858 G132 T S T K Q A K G T K P D S G D
Zebra Danio Brachydanio rerio NP_001005959 212 24583 P118 L R V R E K R P Q R D K S Q A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121472 216 25392 K129 R K G Q K F E K P L K K Q K N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793295 220 24814 K133 P K S A G S V K P S L S N A R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P17890 251 27706 T163 A D D V F T G T G L Q D E N I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 51.1 92.8 N.A. 82.9 83.8 N.A. 77.1 66.3 55.6 47.5 N.A. N.A. 37.6 N.A. 42.6
Protein Similarity: 100 99.5 68.1 96.8 N.A. 91.4 91.9 N.A. 86.5 78.9 73 65.9 N.A. N.A. 58.7 N.A. 60.5
P-Site Identity: 100 93.3 0 80 N.A. 46.6 53.3 N.A. 46.6 13.3 6.6 6.6 N.A. N.A. 20 N.A. 26.6
P-Site Similarity: 100 93.3 26.6 80 N.A. 60 60 N.A. 60 26.6 20 26.6 N.A. N.A. 33.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 47 0 16 31 16 8 8 0 8 0 0 0 0 24 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 31 0 0 0 0 0 0 0 8 16 0 0 62 % D
% Glu: 0 0 0 0 8 8 16 0 8 0 0 0 8 16 0 % E
% Phe: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 31 0 39 8 8 0 0 8 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 8 0 0 0 8 % I
% Lys: 8 62 8 16 8 54 8 16 8 8 16 16 0 16 0 % K
% Leu: 8 0 0 8 0 0 0 8 0 62 8 0 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 39 16 8 8 % N
% Pro: 8 8 8 0 8 0 0 8 24 8 8 0 0 0 0 % P
% Gln: 0 0 0 8 8 0 0 0 8 0 8 0 8 8 0 % Q
% Arg: 8 16 8 8 8 8 8 0 0 8 8 0 8 0 8 % R
% Ser: 8 8 8 8 8 8 0 8 24 8 0 16 31 0 0 % S
% Thr: 8 0 8 16 0 8 0 54 16 0 31 0 31 16 0 % T
% Val: 0 0 8 8 0 0 16 0 0 0 0 8 0 0 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _