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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLR3G All Species: 22.42
Human Site: T138 Identified Species: 41.11
UniProt: O15318 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15318 NP_006458.2 223 25914 T138 K G T P L T N T E D V L K K M
Chimpanzee Pan troglodytes XP_517660 223 25886 T138 K G T S L T N T E D V L K K M
Rhesus Macaque Macaca mulatta XP_001090983 218 25378 R122 R E L K I R V R K L Q K E R I
Dog Lupus familis XP_852150 223 25829 T138 K G T S L T N T A D V L K K I
Cat Felis silvestris
Mouse Mus musculus Q6NXY9 223 25929 S139 K A T S L I N S A D V L K T I
Rat Rattus norvegicus NP_001102938 223 26154 S139 K G T T L M N S T D V L K K I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508505 222 26012 T140 E V T A L T G T T D V L K K I
Chicken Gallus gallus XP_424697 216 24895 N137 K N S E P K S N L D V L K K I
Frog Xenopus laevis NP_001089996 216 24858 S137 A K G T K P D S G D I L K K I
Zebra Danio Brachydanio rerio NP_001005959 212 24583 S123 K R P Q R D K S Q A V P K R A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121472 216 25392 Q134 F E K P L K K Q K N V D V E S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793295 220 24814 N138 S V K P S L S N A R V S K K I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P17890 251 27706 E168 T G T G L Q D E N I G L S M L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 51.1 92.8 N.A. 82.9 83.8 N.A. 77.1 66.3 55.6 47.5 N.A. N.A. 37.6 N.A. 42.6
Protein Similarity: 100 99.5 68.1 96.8 N.A. 91.4 91.9 N.A. 86.5 78.9 73 65.9 N.A. N.A. 58.7 N.A. 60.5
P-Site Identity: 100 93.3 0 80 N.A. 53.3 66.6 N.A. 60 40 26.6 20 N.A. N.A. 20 N.A. 26.6
P-Site Similarity: 100 93.3 40 86.6 N.A. 66.6 80 N.A. 73.3 60 53.3 40 N.A. N.A. 40 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 8 0 0 0 0 24 8 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 16 0 0 62 0 8 0 0 0 % D
% Glu: 8 16 0 8 0 0 0 8 16 0 0 0 8 8 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 39 8 8 0 0 8 0 8 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 8 0 0 0 8 8 0 0 0 62 % I
% Lys: 54 8 16 8 8 16 16 0 16 0 0 8 77 62 0 % K
% Leu: 0 0 8 0 62 8 0 0 8 8 0 70 0 0 8 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 16 % M
% Asn: 0 8 0 0 0 0 39 16 8 8 0 0 0 0 0 % N
% Pro: 0 0 8 24 8 8 0 0 0 0 0 8 0 0 0 % P
% Gln: 0 0 0 8 0 8 0 8 8 0 8 0 0 0 0 % Q
% Arg: 8 8 0 0 8 8 0 8 0 8 0 0 0 16 0 % R
% Ser: 8 0 8 24 8 0 16 31 0 0 0 8 8 0 8 % S
% Thr: 8 0 54 16 0 31 0 31 16 0 0 0 0 8 0 % T
% Val: 0 16 0 0 0 0 8 0 0 0 77 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _