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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLR3G All Species: 26.06
Human Site: T41 Identified Species: 47.78
UniProt: O15318 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15318 NP_006458.2 223 25914 T41 P P P L F P D T D Y K P V P L
Chimpanzee Pan troglodytes XP_517660 223 25886 T41 P P P L F P D T D Y K P V P L
Rhesus Macaque Macaca mulatta XP_001090983 218 25378 L44 P S P L F P P L E F R P V P L
Dog Lupus familis XP_852150 223 25829 T41 P P P L F P D T D Y K P V P L
Cat Felis silvestris
Mouse Mus musculus Q6NXY9 223 25929 T41 P P P L F P D T D Y K P V P L
Rat Rattus norvegicus NP_001102938 223 26154 T41 P P P L F P D T D Y K P V P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508505 222 26012 T41 P P P P F P D T D Y K P A P L
Chicken Gallus gallus XP_424697 216 24895 T42 P P P L F P S T D N K P V P L
Frog Xenopus laevis NP_001089996 216 24858 I40 P L P I F P S I E Y K P V P L
Zebra Danio Brachydanio rerio NP_001005959 212 24583 L38 P T P L F P P L D Q K P V P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121472 216 25392 L42 P P P K Y P S L E Y K P M P L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793295 220 24814 L44 P P P L F P P L E F S P A P L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P17890 251 27706 P42 E F P S I P L P I N G P I T N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 51.1 92.8 N.A. 82.9 83.8 N.A. 77.1 66.3 55.6 47.5 N.A. N.A. 37.6 N.A. 42.6
Protein Similarity: 100 99.5 68.1 96.8 N.A. 91.4 91.9 N.A. 86.5 78.9 73 65.9 N.A. N.A. 58.7 N.A. 60.5
P-Site Identity: 100 100 60 100 N.A. 100 100 N.A. 86.6 86.6 66.6 73.3 N.A. N.A. 60 N.A. 60
P-Site Similarity: 100 100 80 100 N.A. 100 100 N.A. 86.6 86.6 80 73.3 N.A. N.A. 80 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 16 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 47 0 62 0 0 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 31 0 0 0 0 0 0 % E
% Phe: 0 8 0 0 85 0 0 0 0 16 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 8 0 0 8 8 0 0 0 8 0 0 % I
% Lys: 0 0 0 8 0 0 0 0 0 0 77 0 0 0 0 % K
% Leu: 0 8 0 70 0 0 8 31 0 0 0 0 0 0 93 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 16 0 0 0 0 8 % N
% Pro: 93 70 100 8 0 100 24 8 0 0 0 100 0 93 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 0 8 0 8 0 0 24 0 0 0 8 0 0 0 0 % S
% Thr: 0 8 0 0 0 0 0 54 0 0 0 0 0 8 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 70 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 62 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _