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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3G
All Species:
32.73
Human Site:
Y73
Identified Species:
60
UniProt:
O15318
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15318
NP_006458.2
223
25914
Y73
E
T
M
K
R
M
P
Y
F
I
E
T
P
E
E
Chimpanzee
Pan troglodytes
XP_517660
223
25886
Y73
E
T
M
K
R
M
P
Y
F
I
E
T
P
E
E
Rhesus Macaque
Macaca mulatta
XP_001090983
218
25378
Y76
G
A
M
R
Q
L
P
Y
F
I
R
P
A
V
P
Dog
Lupus familis
XP_852150
223
25829
Y73
E
T
M
K
R
M
P
Y
Y
I
E
T
P
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6NXY9
223
25929
Y73
E
T
V
K
R
L
P
Y
F
I
E
P
P
E
E
Rat
Rattus norvegicus
NP_001102938
223
26154
Y73
E
T
V
K
R
L
P
Y
F
I
E
T
P
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508505
222
26012
Y73
E
T
M
R
R
M
P
Y
F
I
D
K
E
K
N
Chicken
Gallus gallus
XP_424697
216
24895
Y74
G
A
M
R
K
M
P
Y
F
L
A
V
E
E
D
Frog
Xenopus laevis
NP_001089996
216
24858
Y72
K
T
V
K
S
L
P
Y
Y
M
G
V
K
A
A
Zebra Danio
Brachydanio rerio
NP_001005959
212
24583
F70
G
A
M
K
T
L
P
F
Y
I
R
P
A
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121472
216
25392
N74
E
Y
M
R
E
S
S
N
N
V
L
P
L
I
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793295
220
24814
Y76
G
H
M
R
D
S
P
Y
C
I
K
P
H
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P17890
251
27706
S74
D
G
P
F
Y
T
G
S
M
S
L
I
I
D
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
51.1
92.8
N.A.
82.9
83.8
N.A.
77.1
66.3
55.6
47.5
N.A.
N.A.
37.6
N.A.
42.6
Protein Similarity:
100
99.5
68.1
96.8
N.A.
91.4
91.9
N.A.
86.5
78.9
73
65.9
N.A.
N.A.
58.7
N.A.
60.5
P-Site Identity:
100
100
33.3
93.3
N.A.
80
86.6
N.A.
60
40
26.6
26.6
N.A.
N.A.
13.3
N.A.
26.6
P-Site Similarity:
100
100
53.3
100
N.A.
93.3
100
N.A.
80
66.6
60
46.6
N.A.
N.A.
26.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
0
0
0
0
0
0
0
0
8
0
16
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
0
0
0
0
0
8
0
0
8
8
% D
% Glu:
54
0
0
0
8
0
0
0
0
0
39
0
16
47
39
% E
% Phe:
0
0
0
8
0
0
0
8
54
0
0
0
0
0
0
% F
% Gly:
31
8
0
0
0
0
8
0
0
0
8
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
70
0
8
8
8
8
% I
% Lys:
8
0
0
54
8
0
0
0
0
0
8
8
8
8
8
% K
% Leu:
0
0
0
0
0
39
0
0
0
8
16
0
8
0
0
% L
% Met:
0
0
70
0
0
39
0
0
8
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
0
0
0
8
8
% N
% Pro:
0
0
8
0
0
0
85
0
0
0
0
39
39
0
16
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
39
47
0
0
0
0
0
16
0
0
0
0
% R
% Ser:
0
0
0
0
8
16
8
8
0
8
0
0
0
0
0
% S
% Thr:
0
54
0
0
8
8
0
0
0
0
0
31
0
0
0
% T
% Val:
0
0
24
0
0
0
0
0
0
8
0
16
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
0
77
24
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _