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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM9SF1
All Species:
29.7
Human Site:
Y460
Identified Species:
59.39
UniProt:
O15321
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15321
NP_001014842.1
606
68861
Y460
E
I
P
P
Q
P
W
Y
K
S
T
V
I
H
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112694
606
68856
Y460
E
I
P
P
Q
P
W
Y
K
S
T
V
I
H
M
Dog
Lupus familis
XP_537385
606
69135
Y460
E
I
P
P
Q
P
W
Y
K
S
T
L
I
H
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBU0
606
68909
Y460
E
I
P
P
Q
P
W
Y
K
S
T
V
I
H
M
Rat
Rattus norvegicus
Q66HF2
589
66900
A443
N
N
A
S
P
F
D
A
P
C
R
T
K
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001121353
557
63869
K412
I
P
R
Q
P
W
Y
K
S
A
P
V
H
M
A
Zebra Danio
Brachydanio rerio
NP_001003550
609
68659
Y463
Q
I
L
Q
Q
P
W
Y
K
H
T
A
V
H
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787683
376
43260
S231
H
W
L
S
I
I
N
S
M
V
L
V
F
L
L
Poplar Tree
Populus trichocarpa
XP_002305925
592
67910
Y446
E
I
P
L
L
P
W
Y
R
K
T
L
P
Q
M
Maize
Zea mays
NP_001151315
593
67658
Y447
E
I
P
P
L
P
W
Y
R
R
T
I
P
Q
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_178306
592
68030
Y446
E
I
P
P
L
P
W
Y
R
S
A
V
P
Q
M
Baker's Yeast
Sacchar. cerevisiae
Q04562
672
76328
Y527
Q
I
P
Y
Q
P
W
Y
L
R
T
A
Q
A
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.8
98.5
N.A.
97.5
94.2
N.A.
N.A.
N.A.
77.2
71.7
N.A.
N.A.
N.A.
N.A.
39.4
Protein Similarity:
100
N.A.
100
98.8
N.A.
98.1
94.8
N.A.
N.A.
N.A.
84.8
81.4
N.A.
N.A.
N.A.
N.A.
49.1
P-Site Identity:
100
N.A.
100
93.3
N.A.
100
0
N.A.
N.A.
N.A.
6.6
60
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
13.3
N.A.
N.A.
N.A.
20
73.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
45.5
46.8
N.A.
47
26
N.A.
Protein Similarity:
62
63.8
N.A.
62.8
45
N.A.
P-Site Identity:
53.3
60
N.A.
66.6
46.6
N.A.
P-Site Similarity:
66.6
73.3
N.A.
73.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
9
0
9
9
17
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% D
% Glu:
59
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
9
0
0
9
42
0
% H
% Ile:
9
75
0
0
9
9
0
0
0
0
0
9
34
0
9
% I
% Lys:
0
0
0
0
0
0
0
9
42
9
0
0
9
0
0
% K
% Leu:
0
0
17
9
25
0
0
0
9
0
9
17
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
67
% M
% Asn:
9
9
0
0
0
0
9
0
0
0
0
0
0
9
0
% N
% Pro:
0
9
67
50
17
75
0
0
9
0
9
0
25
0
0
% P
% Gln:
17
0
0
17
50
0
0
0
0
0
0
0
9
25
0
% Q
% Arg:
0
0
9
0
0
0
0
0
25
17
9
0
0
0
0
% R
% Ser:
0
0
0
17
0
0
0
9
9
42
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
67
9
0
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
9
0
50
9
0
0
% V
% Trp:
0
9
0
0
0
9
75
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
9
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _