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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HMGB3 All Species: 0
Human Site: S105 Identified Species: 0
UniProt: O15347 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15347 NP_005333.2 200 22980 S105 S G F F L F C S E F R P K I K
Chimpanzee Pan troglodytes Q9N1Q7 215 24747
Rhesus Macaque Macaca mulatta XP_001091672 201 23091
Dog Lupus familis XP_538194 201 23063
Cat Felis silvestris
Mouse Mus musculus O54879 200 22991
Rat Rattus norvegicus P63159 215 24875
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509199 201 22939
Chicken Gallus gallus P40618 202 23052
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001116308 213 24538
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24537 393 44916
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09390 235 27301
Sea Urchin Strong. purpuratus P40644 200 22815
Poplar Tree Populus trichocarpa
Maize Zea mays P27347 157 17127
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P11633 99 11557
Red Bread Mold Neurospora crassa Q7S045 103 11590
Conservation
Percent
Protein Identity: 100 50.2 99.5 98 N.A. 97.5 73 N.A. 94.5 92.5 N.A. 66.6 N.A. 26.7 N.A. 32.7 46.5
Protein Similarity: 100 61.4 99.5 98.5 N.A. 99.5 80.9 N.A. 97.5 95.5 N.A. 80.7 N.A. 39.6 N.A. 47.6 60.5
P-Site Identity: 100 0 0 0 N.A. 0 0 N.A. 0 0 N.A. 0 N.A. 0 N.A. 0 0
P-Site Similarity: 100 0 0 0 N.A. 0 0 N.A. 0 0 N.A. 0 N.A. 0 N.A. 0 0
Percent
Protein Identity: N.A. 38 N.A. N.A. 25 29
Protein Similarity: N.A. 49.5 N.A. N.A. 33 37.5
P-Site Identity: N.A. 0 N.A. N.A. 0 0
P-Site Similarity: N.A. 0 N.A. N.A. 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % E
% Phe: 0 0 100 100 0 100 0 0 0 100 0 0 0 0 0 % F
% Gly: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 100 % K
% Leu: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % R
% Ser: 100 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _