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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HMGB3 All Species: 40.3
Human Site: S98 Identified Species: 63.33
UniProt: O15347 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15347 NP_005333.2 200 22980 S98 N A P K R P P S G F F L F C S
Chimpanzee Pan troglodytes Q9N1Q7 215 24747 L129 N A P K R P P L A F F L F C S
Rhesus Macaque Macaca mulatta XP_001091672 201 23091 S98 N A P K R P P S G F F L F C S
Dog Lupus familis XP_538194 201 23063 S98 N A P K R P P S G F F L F C S
Cat Felis silvestris
Mouse Mus musculus O54879 200 22991 S98 N A P K R P P S G F F L F C S
Rat Rattus norvegicus P63159 215 24875 S100 N A P K R P P S A F F L F C S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509199 201 22939 S98 N A P K R P P S G F F L F C S
Chicken Gallus gallus P40618 202 23052 S98 N A P K R P P S A F F L F C S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001116308 213 24538 S97 N A P K R P P S G F F L F C S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24537 393 44916 S276 N A P K R S L S A F F W F C N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09390 235 27301 S140 H A P K R A L S A F F F Y S Q
Sea Urchin Strong. purpuratus P40644 200 22815 S105 D A P K R N L S A F F I F S G
Poplar Tree Populus trichocarpa
Maize Zea mays P27347 157 17127 A89 S L S E S D K A P Y V A K A N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P11633 99 11557 L31 P N A P K R R L S A Y M F F A
Red Bread Mold Neurospora crassa Q7S045 103 11590 F35 R G L S A Y M F F A N E Q R E
Conservation
Percent
Protein Identity: 100 50.2 99.5 98 N.A. 97.5 73 N.A. 94.5 92.5 N.A. 66.6 N.A. 26.7 N.A. 32.7 46.5
Protein Similarity: 100 61.4 99.5 98.5 N.A. 99.5 80.9 N.A. 97.5 95.5 N.A. 80.7 N.A. 39.6 N.A. 47.6 60.5
P-Site Identity: 100 86.6 100 100 N.A. 100 93.3 N.A. 100 93.3 N.A. 100 N.A. 66.6 N.A. 46.6 53.3
P-Site Similarity: 100 86.6 100 100 N.A. 100 93.3 N.A. 100 93.3 N.A. 100 N.A. 73.3 N.A. 60 66.6
Percent
Protein Identity: N.A. 38 N.A. N.A. 25 29
Protein Similarity: N.A. 49.5 N.A. N.A. 33 37.5
P-Site Identity: N.A. 0 N.A. N.A. 6.6 0
P-Site Similarity: N.A. 33.3 N.A. N.A. 33.3 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 80 7 0 7 7 0 7 40 14 0 7 0 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 67 0 % C
% Asp: 7 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 7 0 0 0 0 0 0 0 7 0 0 7 % E
% Phe: 0 0 0 0 0 0 0 7 7 80 80 7 80 7 0 % F
% Gly: 0 7 0 0 0 0 0 0 40 0 0 0 0 0 7 % G
% His: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % I
% Lys: 0 0 0 80 7 0 7 0 0 0 0 0 7 0 0 % K
% Leu: 0 7 7 0 0 0 20 14 0 0 0 60 0 0 0 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 7 0 0 0 % M
% Asn: 67 7 0 0 0 7 0 0 0 0 7 0 0 0 14 % N
% Pro: 7 0 80 7 0 60 60 0 7 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 7 % Q
% Arg: 7 0 0 0 80 7 7 0 0 0 0 0 0 7 0 % R
% Ser: 7 0 7 7 7 7 0 74 7 0 0 0 0 14 60 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % W
% Tyr: 0 0 0 0 0 7 0 0 0 7 7 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _