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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HMGB3 All Species: 36.06
Human Site: T51 Identified Species: 56.67
UniProt: O15347 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15347 NP_005333.2 200 22980 T51 K C S E R W K T M S G K E K S
Chimpanzee Pan troglodytes Q9N1Q7 215 24747 T80 K R S E M W K T I F A K E K G
Rhesus Macaque Macaca mulatta XP_001091672 201 23091 T51 K C S E R W K T M S G K E K S
Dog Lupus familis XP_538194 201 23063 T51 K C S E R W K T M S G K E K S
Cat Felis silvestris
Mouse Mus musculus O54879 200 22991 T51 K C S E R W K T M S S K E K S
Rat Rattus norvegicus P63159 215 24875 T51 K C S E R W K T M S A K E K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509199 201 22939 T51 K C S E R W K T M S G K E K S
Chicken Gallus gallus P40618 202 23052 T51 K C S E R W K T M S S K E K A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001116308 213 24538 A51 R C S G R W K A M T D K E K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24537 393 44916 T221 K C A E R W K T M V D K E K K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09390 235 27301 T87 K C S E K W K T M V D D E K R
Sea Urchin Strong. purpuratus P40644 200 22815 A53 D C S A R W K A L E E K G K G
Poplar Tree Populus trichocarpa
Maize Zea mays P27347 157 17127 P45 P N K P K R A P S A F F V F M
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P11633 99 11557
Red Bread Mold Neurospora crassa Q7S045 103 11590
Conservation
Percent
Protein Identity: 100 50.2 99.5 98 N.A. 97.5 73 N.A. 94.5 92.5 N.A. 66.6 N.A. 26.7 N.A. 32.7 46.5
Protein Similarity: 100 61.4 99.5 98.5 N.A. 99.5 80.9 N.A. 97.5 95.5 N.A. 80.7 N.A. 39.6 N.A. 47.6 60.5
P-Site Identity: 100 60 100 100 N.A. 93.3 86.6 N.A. 100 86.6 N.A. 66.6 N.A. 73.3 N.A. 66.6 46.6
P-Site Similarity: 100 66.6 100 100 N.A. 93.3 86.6 N.A. 100 93.3 N.A. 80 N.A. 80 N.A. 73.3 53.3
Percent
Protein Identity: N.A. 38 N.A. N.A. 25 29
Protein Similarity: N.A. 49.5 N.A. N.A. 33 37.5
P-Site Identity: N.A. 0 N.A. N.A. 0 0
P-Site Similarity: N.A. 13.3 N.A. N.A. 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 0 0 7 14 0 7 14 0 0 0 7 % A
% Cys: 0 74 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 0 0 0 20 7 0 0 0 % D
% Glu: 0 0 0 67 0 0 0 0 0 7 7 0 74 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 7 7 0 7 0 % F
% Gly: 0 0 0 7 0 0 0 0 0 0 27 0 7 0 20 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % I
% Lys: 67 0 7 0 14 0 80 0 0 0 0 74 0 80 7 % K
% Leu: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % L
% Met: 0 0 0 0 7 0 0 0 67 0 0 0 0 0 7 % M
% Asn: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 7 0 0 7 0 0 0 7 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 7 7 0 0 67 7 0 0 0 0 0 0 0 0 7 % R
% Ser: 0 0 74 0 0 0 0 0 7 47 14 0 0 0 40 % S
% Thr: 0 0 0 0 0 0 0 67 0 7 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 14 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 80 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _