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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMGB3
All Species:
30
Human Site:
Y142
Identified Species:
47.14
UniProt:
O15347
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15347
NP_005333.2
200
22980
Y142
N
D
S
E
K
Q
P
Y
I
T
K
A
A
K
L
Chimpanzee
Pan troglodytes
Q9N1Q7
215
24747
Y173
A
A
S
D
K
Q
F
Y
E
K
K
A
A
K
L
Rhesus Macaque
Macaca mulatta
XP_001091672
201
23091
Y142
N
D
S
E
K
Q
P
Y
I
T
K
A
A
K
L
Dog
Lupus familis
XP_538194
201
23063
Y142
S
D
S
E
K
Q
P
Y
N
N
K
A
A
K
L
Cat
Felis silvestris
Mouse
Mus musculus
O54879
200
22991
Y142
S
D
N
E
K
Q
P
Y
V
T
K
A
A
K
L
Rat
Rattus norvegicus
P63159
215
24875
Y144
A
A
D
D
K
Q
P
Y
E
K
K
A
A
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509199
201
22939
Y142
S
D
S
E
K
Q
P
Y
N
N
K
A
A
K
L
Chicken
Gallus gallus
P40618
202
23052
Y142
S
D
G
E
K
Q
P
Y
N
N
K
A
A
K
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001116308
213
24538
F141
T
D
A
N
K
Q
P
F
L
M
K
A
N
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24537
393
44916
Y320
D
P
E
V
K
Q
K
Y
E
S
M
A
E
R
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09390
235
27301
Y184
P
Q
E
T
K
D
M
Y
E
Q
K
A
Q
A
D
Sea Urchin
Strong. purpuratus
P40644
200
22815
F149
T
A
G
E
K
I
P
F
D
K
G
A
A
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P27347
157
17127
E130
K
E
E
E
E
E
D
E
E
E
S
D
K
S
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11633
99
11557
E72
W
K
A
L
T
A
E
E
K
Q
P
Y
E
S
K
Red Bread Mold
Neurospora crassa
Q7S045
103
11590
E76
D
K
Q
R
A
P
Y
E
A
K
A
A
A
D
K
Conservation
Percent
Protein Identity:
100
50.2
99.5
98
N.A.
97.5
73
N.A.
94.5
92.5
N.A.
66.6
N.A.
26.7
N.A.
32.7
46.5
Protein Similarity:
100
61.4
99.5
98.5
N.A.
99.5
80.9
N.A.
97.5
95.5
N.A.
80.7
N.A.
39.6
N.A.
47.6
60.5
P-Site Identity:
100
60
100
80
N.A.
80
60
N.A.
80
73.3
N.A.
53.3
N.A.
26.6
N.A.
26.6
40
P-Site Similarity:
100
66.6
100
86.6
N.A.
100
66.6
N.A.
86.6
80
N.A.
73.3
N.A.
46.6
N.A.
26.6
46.6
Percent
Protein Identity:
N.A.
38
N.A.
N.A.
25
29
Protein Similarity:
N.A.
49.5
N.A.
N.A.
33
37.5
P-Site Identity:
N.A.
6.6
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
6.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
20
14
0
7
7
0
0
7
0
7
87
67
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
47
7
14
0
7
7
0
7
0
0
7
0
7
20
% D
% Glu:
0
7
20
54
7
7
7
20
34
7
0
0
14
0
0
% E
% Phe:
0
0
0
0
0
0
7
14
0
0
0
0
0
0
0
% F
% Gly:
0
0
14
0
0
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
14
0
0
0
0
0
0
% I
% Lys:
7
14
0
0
80
0
7
0
7
27
67
0
7
67
20
% K
% Leu:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
60
% L
% Met:
0
0
0
0
0
0
7
0
0
7
7
0
0
0
0
% M
% Asn:
14
0
7
7
0
0
0
0
20
20
0
0
7
0
0
% N
% Pro:
7
7
0
0
0
7
60
0
0
0
7
0
0
0
0
% P
% Gln:
0
7
7
0
0
67
0
0
0
14
0
0
7
0
0
% Q
% Arg:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% R
% Ser:
27
0
34
0
0
0
0
0
0
7
7
0
0
14
0
% S
% Thr:
14
0
0
7
7
0
0
0
0
20
0
0
0
0
0
% T
% Val:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
67
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _