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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMGB3
All Species:
39.39
Human Site:
Y160
Identified Species:
61.9
UniProt:
O15347
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15347
NP_005333.2
200
22980
Y160
Y
E
K
D
V
A
D
Y
K
S
K
G
K
F
D
Chimpanzee
Pan troglodytes
Q9N1Q7
215
24747
C191
Y
K
K
D
I
A
A
C
R
A
K
G
K
P
N
Rhesus Macaque
Macaca mulatta
XP_001091672
201
23091
Y160
Y
E
K
D
V
A
D
Y
K
S
K
G
K
F
D
Dog
Lupus familis
XP_538194
201
23063
Y160
Y
E
K
D
V
A
D
Y
K
S
K
G
K
F
D
Cat
Felis silvestris
Mouse
Mus musculus
O54879
200
22991
Y160
Y
E
K
D
V
A
D
Y
K
S
K
G
K
F
D
Rat
Rattus norvegicus
P63159
215
24875
Y162
Y
E
K
D
I
A
A
Y
R
A
K
G
K
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509199
201
22939
Y160
Y
E
K
D
V
A
D
Y
K
S
K
G
K
F
D
Chicken
Gallus gallus
P40618
202
23052
Y160
Y
E
K
D
V
A
D
Y
K
S
K
G
K
F
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001116308
213
24538
Y159
Y
Q
K
D
V
A
D
Y
K
T
K
S
K
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24537
393
44916
Y338
Y
E
R
E
M
T
E
Y
K
T
S
G
K
I
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09390
235
27301
Y202
Y
A
D
E
M
R
N
Y
K
A
E
M
Q
K
M
Sea Urchin
Strong. purpuratus
P40644
200
22815
Y167
Y
I
K
A
M
A
E
Y
K
A
K
A
K
P
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P27347
157
17127
G148
N
D
E
D
D
E
E
G
S
E
E
D
E
D
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11633
99
11557
E90
D
K
K
R
Y
E
S
E
K
E
L
Y
N
A
T
Red Bread Mold
Neurospora crassa
Q7S045
103
11590
N94
E
D
E
K
Q
A
Y
N
A
E
A
D
E
E
E
Conservation
Percent
Protein Identity:
100
50.2
99.5
98
N.A.
97.5
73
N.A.
94.5
92.5
N.A.
66.6
N.A.
26.7
N.A.
32.7
46.5
Protein Similarity:
100
61.4
99.5
98.5
N.A.
99.5
80.9
N.A.
97.5
95.5
N.A.
80.7
N.A.
39.6
N.A.
47.6
60.5
P-Site Identity:
100
46.6
100
100
N.A.
100
66.6
N.A.
100
100
N.A.
66.6
N.A.
40
N.A.
20
46.6
P-Site Similarity:
100
80
100
100
N.A.
100
86.6
N.A.
100
100
N.A.
80
N.A.
73.3
N.A.
60
66.6
Percent
Protein Identity:
N.A.
38
N.A.
N.A.
25
29
Protein Similarity:
N.A.
49.5
N.A.
N.A.
33
37.5
P-Site Identity:
N.A.
13.3
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
46.6
N.A.
N.A.
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
74
14
0
7
27
7
7
0
14
7
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
7
14
7
67
7
0
47
0
0
0
0
14
0
7
54
% D
% Glu:
7
54
14
14
0
14
20
7
0
20
14
0
14
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
40
0
% F
% Gly:
0
0
0
0
0
0
0
7
0
0
0
60
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
14
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
0
14
74
7
0
0
0
0
74
0
67
0
74
7
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% L
% Met:
0
0
0
0
20
0
0
0
0
0
0
7
0
0
14
% M
% Asn:
7
0
0
0
0
0
7
7
0
0
0
0
7
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% P
% Gln:
0
7
0
0
7
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
7
7
0
7
0
0
14
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
7
0
7
40
7
7
0
0
0
% S
% Thr:
0
0
0
0
0
7
0
0
0
14
0
0
0
0
7
% T
% Val:
0
0
0
0
47
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
80
0
0
0
7
0
7
74
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _