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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMGB3
All Species:
38.48
Human Site:
Y78
Identified Species:
60.48
UniProt:
O15347
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15347
NP_005333.2
200
22980
Y78
Y
D
R
E
M
K
D
Y
G
P
A
K
G
G
K
Chimpanzee
Pan troglodytes
Q9N1Q7
215
24747
Y107
Y
E
R
E
M
K
T
Y
I
P
P
K
G
E
K
Rhesus Macaque
Macaca mulatta
XP_001091672
201
23091
Y78
Y
D
R
E
M
K
D
Y
G
P
A
K
G
G
K
Dog
Lupus familis
XP_538194
201
23063
Y78
Y
D
R
E
M
K
D
Y
G
P
A
K
G
G
K
Cat
Felis silvestris
Mouse
Mus musculus
O54879
200
22991
Y78
Y
D
R
E
M
K
D
Y
G
P
A
K
G
G
K
Rat
Rattus norvegicus
P63159
215
24875
Y78
Y
E
R
E
M
K
T
Y
I
P
P
K
G
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509199
201
22939
Y78
Y
D
R
E
M
K
D
Y
G
P
A
K
G
G
K
Chicken
Gallus gallus
P40618
202
23052
Y78
Y
D
R
E
M
K
D
Y
G
P
A
K
G
G
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001116308
213
24538
Y78
Y
D
Q
E
M
M
H
Y
M
P
G
K
R
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24537
393
44916
Y248
Y
E
A
E
M
Q
N
Y
V
P
P
K
G
A
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09390
235
27301
A114
Y
Q
A
E
V
S
V
A
A
Y
G
G
E
D
A
Sea Urchin
Strong. purpuratus
P40644
200
22815
Y80
Y
D
R
E
M
Q
S
Y
K
P
P
K
G
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P27347
157
17127
V72
K
N
K
S
V
A
A
V
G
K
A
A
G
D
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11633
99
11557
R16
Q
P
K
E
P
K
K
R
T
T
R
R
K
K
D
Red Bread Mold
Neurospora crassa
Q7S045
103
11590
K20
K
V
E
K
R
R
A
K
K
D
P
N
A
P
K
Conservation
Percent
Protein Identity:
100
50.2
99.5
98
N.A.
97.5
73
N.A.
94.5
92.5
N.A.
66.6
N.A.
26.7
N.A.
32.7
46.5
Protein Similarity:
100
61.4
99.5
98.5
N.A.
99.5
80.9
N.A.
97.5
95.5
N.A.
80.7
N.A.
39.6
N.A.
47.6
60.5
P-Site Identity:
100
66.6
100
100
N.A.
100
60
N.A.
100
100
N.A.
60
N.A.
46.6
N.A.
13.3
66.6
P-Site Similarity:
100
73.3
100
100
N.A.
100
66.6
N.A.
100
100
N.A.
66.6
N.A.
66.6
N.A.
20
73.3
Percent
Protein Identity:
N.A.
38
N.A.
N.A.
25
29
Protein Similarity:
N.A.
49.5
N.A.
N.A.
33
37.5
P-Site Identity:
N.A.
20
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
46.6
N.A.
N.A.
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
0
0
7
14
7
7
0
47
7
7
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
54
0
0
0
0
40
0
0
7
0
0
0
14
7
% D
% Glu:
0
20
7
87
0
0
0
0
0
0
0
0
7
20
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
47
0
14
7
74
47
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
14
0
0
0
0
0
0
% I
% Lys:
14
0
14
7
0
60
7
7
14
7
0
74
7
7
67
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
74
7
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
7
0
0
0
0
7
0
0
0
% N
% Pro:
0
7
0
0
7
0
0
0
0
74
34
0
0
7
0
% P
% Gln:
7
7
7
0
0
14
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
60
0
7
7
0
7
0
0
7
7
7
0
7
% R
% Ser:
0
0
0
7
0
7
7
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
14
0
7
7
0
0
0
0
7
% T
% Val:
0
7
0
0
14
0
7
7
7
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
80
0
0
0
0
0
0
74
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _