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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TP73 All Species: 12.12
Human Site: Y121 Identified Species: 29.63
UniProt: O15350 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15350 NP_001119712.1 636 69623 Y121 V I P S N T D Y P G P H H F E
Chimpanzee Pan troglodytes XP_001160425 586 65734 V121 T C P I Q I K V M T P P P Q G
Rhesus Macaque Macaca mulatta P56424 393 43637
Dog Lupus familis XP_546740 1086 116755 Y567 A I P S N T D Y P G P H H F D
Cat Felis silvestris
Mouse Mus musculus Q9JJP2 631 69077 V121 P G P H H F E V T F Q Q S S T
Rat Rattus norvegicus Q9JJP6 680 76742 Y171 A I P S N T D Y P G P H S F D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512581 688 77295 Y180 A I P S N T D Y P G P H S F D
Chicken Gallus gallus P10360 367 40151
Frog Xenopus laevis P07193 363 40674
Zebra Danio Brachydanio rerio P79734 373 41881
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.8 29.8 53.9 N.A. 89.4 53.8 N.A. 53.4 29.5 29 29.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 69.3 40.8 56.6 N.A. 93.5 68.8 N.A. 67.7 40.7 40.8 41.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 0 86.6 N.A. 6.6 80 N.A. 80 0 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 0 93.3 N.A. 20 86.6 N.A. 86.6 0 0 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 30 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 40 0 0 0 0 0 0 0 30 % D
% Glu: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 10 0 0 0 10 0 0 0 40 0 % F
% Gly: 0 10 0 0 0 0 0 0 0 40 0 0 0 0 10 % G
% His: 0 0 0 10 10 0 0 0 0 0 0 40 20 0 0 % H
% Ile: 0 40 0 10 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 40 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 60 0 0 0 0 0 40 0 50 10 10 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 10 10 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 40 0 0 0 0 0 0 0 0 30 10 0 % S
% Thr: 10 0 0 0 0 40 0 0 10 10 0 0 0 0 10 % T
% Val: 10 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 40 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _