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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FOXN1 All Species: 20.3
Human Site: T497 Identified Species: 44.67
UniProt: O15353 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15353 NP_003584.2 648 68925 T497 D S P L P A H T P P S H S A K
Chimpanzee Pan troglodytes XP_001146066 648 68707 T497 D S P L P A H T P P S H S A K
Rhesus Macaque Macaca mulatta XP_001107016 648 68848 T497 D S P L P A H T P P S H S A K
Dog Lupus familis XP_548288 643 68251 T495 D S P L P A N T P P S H S A K
Cat Felis silvestris
Mouse Mus musculus Q61575 648 69227 T497 D S P L P A H T P P S H G A K
Rat Rattus norvegicus Q63247 421 45548 K275 G R L G H K R K Q P L P K R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507128 553 60380 Q407 P A K I D K M Q E E L Q K W K
Chicken Gallus gallus XP_415816 645 71194 T489 S S A L M P Q T P D H Q T M F
Frog Xenopus laevis Q3BJS1 506 55901 T359 P L H H Q I Q T Q A R I A S G
Zebra Danio Brachydanio rerio NP_997738 565 62450 P419 H Q P S V G H P S S P R T G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001194048 550 59488 P404 A L S R I S T P K S S P R E S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.1 97 91 N.A. 86.1 22.6 N.A. 47.5 56.6 33.6 36.5 N.A. N.A. N.A. N.A. 26
Protein Similarity: 100 98.9 97.9 93 N.A. 90.9 33 N.A. 55.5 67.7 45.9 48.9 N.A. N.A. N.A. N.A. 40.4
P-Site Identity: 100 100 100 93.3 N.A. 93.3 6.6 N.A. 6.6 26.6 6.6 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 6.6 N.A. 20 33.3 20 20 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 0 0 46 0 0 0 10 0 0 10 46 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 46 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 10 10 0 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 10 0 0 10 0 10 0 0 0 0 0 0 10 10 10 % G
% His: 10 0 10 10 10 0 46 0 0 0 10 46 0 0 0 % H
% Ile: 0 0 0 10 10 10 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 10 0 0 19 0 10 10 0 0 0 19 0 55 % K
% Leu: 0 19 10 55 0 0 0 0 0 0 19 0 0 0 0 % L
% Met: 0 0 0 0 10 0 10 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 19 0 55 0 46 10 0 19 55 55 10 19 0 0 0 % P
% Gln: 0 10 0 0 10 0 19 10 19 0 0 19 0 0 0 % Q
% Arg: 0 10 0 10 0 0 10 0 0 0 10 10 10 10 0 % R
% Ser: 10 55 10 10 0 10 0 0 10 19 55 0 37 10 19 % S
% Thr: 0 0 0 0 0 0 10 64 0 0 0 0 19 0 0 % T
% Val: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _