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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOX12
All Species:
0.91
Human Site:
S130
Identified Species:
2
UniProt:
O15370
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15370
NP_008874.2
315
34122
S130
R
P
R
P
P
G
G
S
G
G
G
S
R
L
K
Chimpanzee
Pan troglodytes
Q9BG89
509
56105
Q195
E
A
E
E
A
T
E
Q
T
H
I
S
P
N
A
Rhesus Macaque
Macaca mulatta
XP_001107541
231
25683
E94
I
P
F
V
R
E
A
E
R
L
R
L
K
H
M
Dog
Lupus familis
XP_542944
321
34466
G130
R
P
R
P
P
G
G
G
G
G
G
G
G
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q04890
314
34064
G130
R
P
R
P
P
G
G
G
G
G
G
S
R
L
K
Rat
Rattus norvegicus
P0C1G9
395
42581
D139
P
S
A
G
Q
S
P
D
K
S
A
A
G
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P48435
396
43485
E139
P
N
A
G
Q
S
P
E
K
N
A
P
G
G
G
Frog
Xenopus laevis
P40650
374
41945
S135
K
S
P
T
L
A
Q
S
P
E
K
S
P
K
S
Zebra Danio
Brachydanio rerio
Q6P0E1
315
34680
L128
K
Y
T
L
P
G
G
L
L
A
P
G
G
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40656
669
72724
G277
K
P
N
Q
D
A
D
G
C
E
A
R
N
D
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798084
367
40653
K148
A
A
K
T
T
S
S
K
P
K
A
N
K
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.3
72
95.3
N.A.
94.9
42.5
N.A.
N.A.
41.1
40.3
25.7
N.A.
23
N.A.
N.A.
34
Protein Similarity:
100
35.9
72
95.6
N.A.
96.8
51.9
N.A.
N.A.
50.7
52.6
40
N.A.
31.2
N.A.
N.A.
45.7
P-Site Identity:
100
6.6
6.6
66.6
N.A.
93.3
6.6
N.A.
N.A.
0
13.3
20
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
6.6
13.3
66.6
N.A.
93.3
13.3
N.A.
N.A.
0
20
26.6
N.A.
13.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
19
0
10
19
10
0
0
10
37
10
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
10
10
0
0
0
0
0
10
0
% D
% Glu:
10
0
10
10
0
10
10
19
0
19
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
19
0
37
37
28
28
28
28
19
37
19
28
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
28
0
10
0
0
0
0
10
19
10
10
0
19
10
37
% K
% Leu:
0
0
0
10
10
0
0
10
10
10
0
10
0
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
10
0
0
0
0
0
0
10
0
10
10
19
0
% N
% Pro:
19
46
10
28
37
0
19
0
19
0
10
10
19
10
0
% P
% Gln:
0
0
0
10
19
0
10
10
0
0
0
0
0
0
0
% Q
% Arg:
28
0
28
0
10
0
0
0
10
0
10
10
19
0
0
% R
% Ser:
0
19
0
0
0
28
10
19
0
10
0
37
0
0
10
% S
% Thr:
0
0
10
19
10
10
0
0
10
0
0
0
0
0
10
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _