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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOX12 All Species: 27.88
Human Site: T292 Identified Species: 61.33
UniProt: O15370 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15370 NP_008874.2 315 34122 T292 F E F P D Y C T P E V T E M I
Chimpanzee Pan troglodytes Q9BG89 509 56105 T460 S H A A G Q G T G L Y S T F T
Rhesus Macaque Macaca mulatta XP_001107541 231 25683 T208 F E F P D Y C T P E V T E M I
Dog Lupus familis XP_542944 321 34466 T298 F E F P D Y C T P E V T E M I
Cat Felis silvestris
Mouse Mus musculus Q04890 314 34064 T291 F E F P D Y C T P E V T E M I
Rat Rattus norvegicus P0C1G9 395 42581 T372 F E F P D Y C T P E L S E M I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P48435 396 43485 T373 F E F P D Y C T P E L S E M I
Frog Xenopus laevis P40650 374 41945 T351 F D F P D Y C T P E L S E M I
Zebra Danio Brachydanio rerio Q6P0E1 315 34680 R289 Q D Q S A Q S R L H M S Q H Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40656 669 72724 V619 Q Q D Y T G S V I E T H N D L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798084 367 40653 F319 S E F N N F N F G S V P D D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.3 72 95.3 N.A. 94.9 42.5 N.A. N.A. 41.1 40.3 25.7 N.A. 23 N.A. N.A. 34
Protein Similarity: 100 35.9 72 95.6 N.A. 96.8 51.9 N.A. N.A. 50.7 52.6 40 N.A. 31.2 N.A. N.A. 45.7
P-Site Identity: 100 6.6 100 100 N.A. 100 86.6 N.A. N.A. 86.6 80 0 N.A. 6.6 N.A. N.A. 20
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. N.A. 100 100 26.6 N.A. 20 N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 10 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 64 0 0 0 0 0 0 0 0 % C
% Asp: 0 19 10 0 64 0 0 0 0 0 0 0 10 19 0 % D
% Glu: 0 64 0 0 0 0 0 0 0 73 0 0 64 0 0 % E
% Phe: 64 0 73 0 0 10 0 10 0 0 0 0 0 10 0 % F
% Gly: 0 0 0 0 10 10 10 0 19 0 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 10 0 10 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 64 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 10 10 28 0 0 0 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 64 0 % M
% Asn: 0 0 0 10 10 0 10 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 64 0 0 0 0 64 0 0 10 0 0 0 % P
% Gln: 19 10 10 0 0 19 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % R
% Ser: 19 0 0 10 0 0 19 0 0 10 0 46 0 0 0 % S
% Thr: 0 0 0 0 10 0 0 73 0 0 10 37 10 0 10 % T
% Val: 0 0 0 0 0 0 0 10 0 0 46 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 64 0 0 0 0 10 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _