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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3D
All Species:
22.42
Human Site:
S213
Identified Species:
37.95
UniProt:
O15371
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15371
NP_003744.1
548
63973
S213
F
D
R
I
T
T
R
S
E
K
P
L
R
S
I
Chimpanzee
Pan troglodytes
XP_001158987
547
63723
S213
F
D
R
I
T
T
R
S
E
K
P
L
R
S
I
Rhesus Macaque
Macaca mulatta
XP_001083790
547
63709
S213
F
D
R
I
T
T
R
S
E
K
P
L
R
S
I
Dog
Lupus familis
XP_850595
548
63914
S213
F
D
R
I
T
T
R
S
E
K
P
L
R
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q6AYK8
548
63970
S213
F
D
R
I
T
T
R
S
E
K
P
L
R
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506069
668
76273
N213
F
D
R
V
T
T
R
N
E
K
T
L
R
S
I
Chicken
Gallus gallus
XP_001234643
699
80199
N367
F
D
R
I
T
T
R
N
E
K
L
L
R
S
I
Frog
Xenopus laevis
Q7ZTM9
550
63926
N216
F
D
R
I
T
T
R
N
E
R
P
L
R
S
I
Zebra Danio
Brachydanio rerio
Q6TH15
552
64071
N216
F
D
R
I
T
T
R
N
E
K
P
L
K
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCK0
560
63779
N219
Y
D
R
I
N
V
K
N
E
K
P
L
Q
K
I
Honey Bee
Apis mellifera
XP_393057
562
64634
S229
Y
D
R
V
N
V
K
S
E
K
P
L
Q
R
I
Nematode Worm
Caenorhab. elegans
P30642
570
64271
S233
D
R
V
S
V
K
N
S
I
P
L
Q
R
C
A
Sea Urchin
Strong. purpuratus
XP_796913
549
63524
K213
M
F
D
R
V
T
T
K
T
E
K
R
L
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P56820
591
66706
R237
R
I
T
P
K
N
E
R
R
L
E
R
F
K
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.2
99
N.A.
N.A.
98.9
N.A.
73.8
72.5
89.4
90.4
N.A.
56.7
60.5
45.7
63.2
Protein Similarity:
100
99.4
99.4
99.8
N.A.
N.A.
99.8
N.A.
77.4
76.3
96.7
96.7
N.A.
73.3
77
63.5
82.3
P-Site Identity:
100
100
100
100
N.A.
N.A.
100
N.A.
80
86.6
86.6
86.6
N.A.
53.3
53.3
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
N.A.
100
N.A.
93.3
93.3
100
100
N.A.
80
80
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
79
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
79
8
8
0
0
0
0
% E
% Phe:
65
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
65
0
0
0
0
8
0
0
0
0
0
79
% I
% Lys:
0
0
0
0
8
8
15
8
0
72
8
0
8
15
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
8
15
79
8
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
15
8
8
36
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
8
0
0
0
0
0
8
65
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
15
0
0
% Q
% Arg:
8
8
79
8
0
0
65
8
8
8
0
15
65
8
8
% R
% Ser:
0
0
0
8
0
0
0
50
0
0
0
0
0
65
0
% S
% Thr:
0
0
8
0
65
72
8
0
8
0
8
0
0
0
0
% T
% Val:
0
0
8
15
15
15
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _