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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3H
All Species:
29.09
Human Site:
S161
Identified Species:
45.71
UniProt:
O15372
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15372
NP_003747.1
352
39930
S161
P
I
K
T
A
Q
G
S
L
S
L
K
A
Y
R
Chimpanzee
Pan troglodytes
XP_001139607
359
40758
S161
P
I
K
T
A
Q
G
S
L
S
L
K
A
Y
R
Rhesus Macaque
Macaca mulatta
XP_001093853
352
39928
S161
P
I
K
T
A
Q
G
S
L
S
L
K
A
Y
R
Dog
Lupus familis
XP_532315
352
39868
S161
P
I
K
T
A
Q
G
S
L
S
L
K
A
Y
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91WK2
352
39814
S161
P
I
K
T
A
Q
G
S
L
S
L
K
A
Y
R
Rat
Rattus norvegicus
Q6P9U8
352
39887
S161
P
I
K
T
A
Q
G
S
L
S
L
K
A
Y
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLE6
348
39518
S157
P
I
K
T
A
Q
G
S
L
S
L
K
A
Y
R
Frog
Xenopus laevis
Q5PPY6
334
38372
A148
Q
G
S
L
S
L
K
A
Y
R
L
T
P
K
L
Zebra Danio
Brachydanio rerio
Q6AXJ2
335
38578
A149
Q
G
S
L
C
L
K
A
Y
R
L
T
P
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U9Q4
338
38389
P152
L
K
A
Y
R
L
T
P
Q
A
I
Q
M
Y
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01974
365
40946
Q154
P
I
K
T
R
Q
G
Q
L
S
L
R
A
W
R
Sea Urchin
Strong. purpuratus
XP_780589
327
37161
A141
K
S
S
L
S
L
K
A
Y
R
L
T
E
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001140776
343
38915
A157
Q
G
V
L
A
L
K
A
L
K
L
T
D
S
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5Z2
337
38354
A151
L
G
V
L
A
L
K
A
L
K
L
S
D
S
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S9Y9
359
40352
T171
Y
K
E
A
K
F
T
T
E
S
L
R
N
S
K
Conservation
Percent
Protein Identity:
100
98
99.4
98.3
N.A.
97.1
97.7
N.A.
N.A.
89.4
79.5
80.6
N.A.
43.7
N.A.
30.6
54.2
Protein Similarity:
100
98
99.4
98.5
N.A.
98.3
98.8
N.A.
N.A.
94.3
88
88
N.A.
65
N.A.
51.2
72.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
6.6
6.6
N.A.
6.6
N.A.
73.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
20
13.3
N.A.
33.3
N.A.
86.6
20
Percent
Protein Identity:
N.A.
40
N.A.
39.7
N.A.
27.3
Protein Similarity:
N.A.
61.3
N.A.
59.6
N.A.
50.4
P-Site Identity:
N.A.
20
N.A.
20
N.A.
13.3
P-Site Similarity:
N.A.
26.6
N.A.
26.6
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
60
0
0
34
0
7
0
0
54
0
7
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% D
% Glu:
0
0
7
0
0
0
0
0
7
0
0
0
7
0
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
14
% F
% Gly:
0
27
0
0
0
0
54
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
54
0
0
0
0
0
0
0
0
7
0
0
0
0
% I
% Lys:
7
14
54
0
7
0
34
0
0
14
0
47
0
14
14
% K
% Leu:
14
0
0
34
0
40
0
0
67
0
94
0
0
0
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
54
0
0
0
0
0
0
7
0
0
0
0
14
0
0
% P
% Gln:
20
0
0
0
0
54
0
7
7
0
0
7
0
7
0
% Q
% Arg:
0
0
0
0
14
0
0
0
0
20
0
14
0
0
54
% R
% Ser:
0
7
20
0
14
0
0
47
0
60
0
7
0
20
0
% S
% Thr:
0
0
0
54
0
0
14
7
0
0
0
27
0
0
0
% T
% Val:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
7
0
0
7
0
0
0
0
20
0
0
0
0
54
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _