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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3H
All Species:
19.39
Human Site:
S17
Identified Species:
30.48
UniProt:
O15372
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15372
NP_003747.1
352
39930
S17
S
T
A
T
S
S
S
S
T
A
G
A
A
G
K
Chimpanzee
Pan troglodytes
XP_001139607
359
40758
S17
S
T
A
T
S
S
S
S
T
A
G
A
A
G
K
Rhesus Macaque
Macaca mulatta
XP_001093853
352
39928
S17
S
T
A
T
S
S
S
S
T
T
G
G
A
G
K
Dog
Lupus familis
XP_532315
352
39868
S17
S
A
A
T
S
S
S
S
T
T
G
P
A
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91WK2
352
39814
S17
S
T
A
T
S
S
G
S
A
G
G
A
V
G
K
Rat
Rattus norvegicus
Q6P9U8
352
39887
S17
S
T
A
T
S
S
S
S
T
G
G
A
V
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLE6
348
39518
A17
A
A
G
G
G
F
G
A
S
K
G
K
G
K
A
Frog
Xenopus laevis
Q5PPY6
334
38372
P12
K
E
T
G
N
T
A
P
I
A
E
T
A
V
K
Zebra Danio
Brachydanio rerio
Q6AXJ2
335
38578
N13
E
S
A
A
S
G
S
N
P
L
D
F
P
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U9Q4
338
38389
D16
A
A
R
T
E
D
S
D
N
T
I
N
Y
V
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01974
365
40946
L17
P
S
V
K
H
I
L
L
D
S
L
V
V
M
K
Sea Urchin
Strong. purpuratus
XP_780589
327
37161
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001140776
343
38915
V17
V
R
S
F
L
Q
A
V
S
T
V
T
E
E
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5Z2
337
38354
D15
F
L
Q
A
I
S
K
D
E
A
V
A
P
P
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S9Y9
359
40352
A35
S
T
S
F
P
T
V
A
T
G
S
I
V
G
M
Conservation
Percent
Protein Identity:
100
98
99.4
98.3
N.A.
97.1
97.7
N.A.
N.A.
89.4
79.5
80.6
N.A.
43.7
N.A.
30.6
54.2
Protein Similarity:
100
98
99.4
98.5
N.A.
98.3
98.8
N.A.
N.A.
94.3
88
88
N.A.
65
N.A.
51.2
72.1
P-Site Identity:
100
100
86.6
80
N.A.
73.3
86.6
N.A.
N.A.
6.6
20
26.6
N.A.
13.3
N.A.
6.6
0
P-Site Similarity:
100
100
86.6
80
N.A.
73.3
86.6
N.A.
N.A.
26.6
40
40
N.A.
26.6
N.A.
20
0
Percent
Protein Identity:
N.A.
40
N.A.
39.7
N.A.
27.3
Protein Similarity:
N.A.
61.3
N.A.
59.6
N.A.
50.4
P-Site Identity:
N.A.
0
N.A.
20
N.A.
26.6
P-Site Similarity:
N.A.
20
N.A.
20
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
20
47
14
0
0
14
14
7
27
0
34
34
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
14
7
0
7
0
0
0
0
% D
% Glu:
7
7
0
0
7
0
0
0
7
0
7
0
7
7
0
% E
% Phe:
7
0
0
14
0
7
0
0
0
0
0
7
0
0
0
% F
% Gly:
0
0
7
14
7
7
14
0
0
20
47
7
7
47
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
7
0
0
7
0
7
7
0
0
0
% I
% Lys:
7
0
0
7
0
0
7
0
0
7
0
7
0
7
60
% K
% Leu:
0
7
0
0
7
0
7
7
0
7
7
0
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% M
% Asn:
0
0
0
0
7
0
0
7
7
0
0
7
0
0
0
% N
% Pro:
7
0
0
0
7
0
0
7
7
0
0
7
14
7
0
% P
% Gln:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
7
% Q
% Arg:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
47
14
14
0
47
47
47
40
14
7
7
0
0
0
0
% S
% Thr:
0
40
7
47
0
14
0
0
40
27
0
14
0
0
7
% T
% Val:
7
0
7
0
0
0
7
7
0
0
14
7
27
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _