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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3H
All Species:
27.27
Human Site:
S222
Identified Species:
42.86
UniProt:
O15372
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15372
NP_003747.1
352
39930
S222
M
W
E
L
E
K
K
S
A
V
A
D
K
H
E
Chimpanzee
Pan troglodytes
XP_001139607
359
40758
S222
M
W
E
L
E
K
K
S
A
V
A
D
K
H
E
Rhesus Macaque
Macaca mulatta
XP_001093853
352
39928
S222
M
W
E
L
E
K
K
S
A
V
A
D
K
H
E
Dog
Lupus familis
XP_532315
352
39868
S222
M
W
E
L
E
K
K
S
A
V
A
D
K
H
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91WK2
352
39814
S222
M
W
E
L
E
K
K
S
A
V
A
D
K
H
E
Rat
Rattus norvegicus
Q6P9U8
352
39887
S222
M
W
E
L
E
K
K
S
A
V
A
D
K
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLE6
348
39518
S218
L
W
E
L
E
K
K
S
A
V
A
D
R
H
E
Frog
Xenopus laevis
Q5PPY6
334
38372
K209
K
K
A
P
V
T
E
K
H
E
L
L
N
L
S
Zebra Danio
Brachydanio rerio
Q6AXJ2
335
38578
K210
E
K
S
T
L
A
D
K
H
E
L
L
N
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U9Q4
338
38389
D213
D
K
G
H
N
F
L
D
L
G
T
A
T
V
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01974
365
40946
K215
M
S
E
L
S
L
A
K
S
C
S
S
D
K
Y
Sea Urchin
Strong. purpuratus
XP_780589
327
37161
D202
G
L
S
T
A
G
D
D
N
F
L
S
L
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001140776
343
38915
C218
P
E
S
P
V
T
Q
C
D
L
D
R
L
K
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5Z2
337
38354
G212
T
D
T
P
V
S
Q
G
D
Y
D
R
L
H
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S9Y9
359
40352
A232
R
D
P
V
Q
I
P
A
H
P
G
F
E
S
L
Conservation
Percent
Protein Identity:
100
98
99.4
98.3
N.A.
97.1
97.7
N.A.
N.A.
89.4
79.5
80.6
N.A.
43.7
N.A.
30.6
54.2
Protein Similarity:
100
98
99.4
98.5
N.A.
98.3
98.8
N.A.
N.A.
94.3
88
88
N.A.
65
N.A.
51.2
72.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
0
0
N.A.
0
N.A.
20
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
6.6
0
N.A.
0
N.A.
33.3
0
Percent
Protein Identity:
N.A.
40
N.A.
39.7
N.A.
27.3
Protein Similarity:
N.A.
61.3
N.A.
59.6
N.A.
50.4
P-Site Identity:
N.A.
0
N.A.
6.6
N.A.
0
P-Site Similarity:
N.A.
13.3
N.A.
13.3
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
7
7
7
47
0
47
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% C
% Asp:
7
14
0
0
0
0
14
14
14
0
14
47
7
0
0
% D
% Glu:
7
7
54
0
47
0
7
0
0
14
0
0
7
0
47
% E
% Phe:
0
0
0
0
0
7
0
0
0
7
0
7
0
0
0
% F
% Gly:
7
0
7
0
0
7
0
7
0
7
7
0
0
0
0
% G
% His:
0
0
0
7
0
0
0
0
20
0
0
0
0
54
0
% H
% Ile:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
20
0
0
0
47
47
20
0
0
0
0
40
14
0
% K
% Leu:
7
7
0
54
7
7
7
0
7
7
20
14
20
14
20
% L
% Met:
47
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
7
0
0
0
14
0
0
% N
% Pro:
7
0
7
20
0
0
7
0
0
7
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
0
14
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
0
0
0
0
0
0
14
7
0
0
% R
% Ser:
0
7
20
0
7
7
0
47
7
0
7
14
0
14
20
% S
% Thr:
7
0
7
14
0
14
0
0
0
0
7
0
7
0
7
% T
% Val:
0
0
0
7
20
0
0
0
0
47
0
0
0
7
0
% V
% Trp:
0
47
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _