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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3H
All Species:
22.73
Human Site:
T8
Identified Species:
35.71
UniProt:
O15372
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15372
NP_003747.1
352
39930
T8
M
A
S
R
K
E
G
T
G
S
T
A
T
S
S
Chimpanzee
Pan troglodytes
XP_001139607
359
40758
T8
M
A
S
R
K
E
G
T
G
S
T
A
T
S
S
Rhesus Macaque
Macaca mulatta
XP_001093853
352
39928
T8
M
A
S
R
K
E
G
T
G
S
T
A
T
S
S
Dog
Lupus familis
XP_532315
352
39868
A8
M
A
S
R
K
E
G
A
G
S
A
A
T
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91WK2
352
39814
T8
M
A
S
R
K
E
G
T
G
S
T
A
T
S
S
Rat
Rattus norvegicus
Q6P9U8
352
39887
T8
M
A
S
R
K
E
G
T
G
S
T
A
T
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLE6
348
39518
S8
M
A
S
R
K
E
G
S
G
A
A
G
G
G
F
Frog
Xenopus laevis
Q5PPY6
334
38372
Zebra Danio
Brachydanio rerio
Q6AXJ2
335
38578
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U9Q4
338
38389
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01974
365
40946
T8
M
S
T
A
V
T
I
T
A
P
S
V
K
H
I
Sea Urchin
Strong. purpuratus
XP_780589
327
37161
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001140776
343
38915
G8
M
A
N
S
A
A
P
G
G
V
R
S
F
L
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5Z2
337
38354
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S9Y9
359
40352
H26
V
V
M
K
I
V
K
H
C
S
T
S
F
P
T
Conservation
Percent
Protein Identity:
100
98
99.4
98.3
N.A.
97.1
97.7
N.A.
N.A.
89.4
79.5
80.6
N.A.
43.7
N.A.
30.6
54.2
Protein Similarity:
100
98
99.4
98.5
N.A.
98.3
98.8
N.A.
N.A.
94.3
88
88
N.A.
65
N.A.
51.2
72.1
P-Site Identity:
100
100
100
86.6
N.A.
100
100
N.A.
N.A.
53.3
0
0
N.A.
0
N.A.
13.3
0
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
N.A.
66.6
0
0
N.A.
0
N.A.
33.3
0
Percent
Protein Identity:
N.A.
40
N.A.
39.7
N.A.
27.3
Protein Similarity:
N.A.
61.3
N.A.
59.6
N.A.
50.4
P-Site Identity:
N.A.
20
N.A.
0
N.A.
13.3
P-Site Similarity:
N.A.
33.3
N.A.
0
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
0
7
7
7
0
7
7
7
14
40
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
47
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
7
% F
% Gly:
0
0
0
0
0
0
47
7
54
0
0
7
7
7
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
7
% I
% Lys:
0
0
0
7
47
0
7
0
0
0
0
0
7
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% L
% Met:
60
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
7
0
0
0
7
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
0
0
0
47
0
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
0
7
47
7
0
0
0
7
0
47
7
14
0
40
40
% S
% Thr:
0
0
7
0
0
7
0
40
0
0
40
0
40
0
7
% T
% Val:
7
7
0
0
7
7
0
0
0
7
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _