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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3H
All Species:
34.24
Human Site:
Y152
Identified Species:
53.81
UniProt:
O15372
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15372
NP_003747.1
352
39930
Y152
E
E
S
V
V
L
I
Y
D
P
I
K
T
A
Q
Chimpanzee
Pan troglodytes
XP_001139607
359
40758
Y152
E
E
S
V
V
L
I
Y
D
P
I
K
T
A
Q
Rhesus Macaque
Macaca mulatta
XP_001093853
352
39928
Y152
E
E
S
V
V
L
I
Y
D
P
I
K
T
A
Q
Dog
Lupus familis
XP_532315
352
39868
Y152
E
E
S
V
V
L
I
Y
D
P
I
K
T
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q91WK2
352
39814
Y152
E
E
S
V
V
L
I
Y
D
P
I
K
T
A
Q
Rat
Rattus norvegicus
Q6P9U8
352
39887
Y152
E
E
S
V
V
L
I
Y
D
P
I
K
T
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLE6
348
39518
Y148
E
E
S
V
V
L
I
Y
D
P
I
K
T
A
Q
Frog
Xenopus laevis
Q5PPY6
334
38372
T139
L
I
Y
D
P
I
K
T
S
Q
G
S
L
S
L
Zebra Danio
Brachydanio rerio
Q6AXJ2
335
38578
T140
L
I
Y
D
P
L
K
T
A
Q
G
S
L
C
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U9Q4
338
38389
L143
Q
K
S
S
R
G
F
L
C
L
K
A
Y
R
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01974
365
40946
Y145
P
E
N
V
V
L
I
Y
D
P
I
K
T
R
Q
Sea Urchin
Strong. purpuratus
XP_780589
327
37161
T132
L
I
Y
D
P
V
K
T
S
K
S
S
L
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001140776
343
38915
S148
I
V
Y
D
P
S
R
S
S
Q
G
V
L
A
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5Z2
337
38354
A142
I
I
Y
D
P
S
K
A
D
L
G
V
L
A
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S9Y9
359
40352
T162
K
L
S
P
E
F
M
T
A
Y
K
E
A
K
F
Conservation
Percent
Protein Identity:
100
98
99.4
98.3
N.A.
97.1
97.7
N.A.
N.A.
89.4
79.5
80.6
N.A.
43.7
N.A.
30.6
54.2
Protein Similarity:
100
98
99.4
98.5
N.A.
98.3
98.8
N.A.
N.A.
94.3
88
88
N.A.
65
N.A.
51.2
72.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
0
6.6
N.A.
6.6
N.A.
80
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
13.3
6.6
N.A.
20
N.A.
86.6
13.3
Percent
Protein Identity:
N.A.
40
N.A.
39.7
N.A.
27.3
Protein Similarity:
N.A.
61.3
N.A.
59.6
N.A.
50.4
P-Site Identity:
N.A.
6.6
N.A.
13.3
N.A.
6.6
P-Site Similarity:
N.A.
6.6
N.A.
13.3
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
14
0
0
7
7
60
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
7
0
% C
% Asp:
0
0
0
34
0
0
0
0
60
0
0
0
0
0
0
% D
% Glu:
47
54
0
0
7
0
0
0
0
0
0
7
0
0
0
% E
% Phe:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
7
% F
% Gly:
0
0
0
0
0
7
0
0
0
0
27
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
14
27
0
0
0
7
54
0
0
0
54
0
0
0
0
% I
% Lys:
7
7
0
0
0
0
27
0
0
7
14
54
0
7
0
% K
% Leu:
20
7
0
0
0
60
0
7
0
14
0
0
34
0
40
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
7
0
0
7
34
0
0
0
0
54
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
0
20
0
0
0
0
54
% Q
% Arg:
0
0
0
0
7
0
7
0
0
0
0
0
0
14
0
% R
% Ser:
0
0
60
7
0
14
0
7
20
0
7
20
0
14
0
% S
% Thr:
0
0
0
0
0
0
0
27
0
0
0
0
54
0
0
% T
% Val:
0
7
0
54
54
7
0
0
0
0
0
14
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
34
0
0
0
0
54
0
7
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _