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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC16A4
All Species:
4.85
Human Site:
S259
Identified Species:
11.85
UniProt:
O15374
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15374
NP_004687.1
487
54022
S259
L
T
V
S
Q
N
Q
S
E
E
F
Y
N
G
P
Chimpanzee
Pan troglodytes
XP_525180
284
31172
E57
E
E
F
E
G
T
S
E
Q
I
G
W
I
G
S
Rhesus Macaque
Macaca mulatta
XP_001100728
486
53832
S258
L
I
V
S
Q
N
Q
S
E
E
F
Y
N
G
P
Dog
Lupus familis
XP_537034
482
53155
R255
G
Q
P
G
T
S
L
R
V
S
Q
N
K
N
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGC3
486
53133
V258
S
D
F
V
V
L
A
V
S
V
L
F
M
A
Y
Rat
Rattus norvegicus
Q63344
489
53039
F262
L
S
G
N
V
V
L
F
L
G
M
F
A
P
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508367
453
50226
L226
G
S
N
Q
H
R
E
L
P
P
T
E
E
E
T
Chicken
Gallus gallus
Q5ZJU0
507
55926
E262
L
S
S
I
N
V
D
E
K
D
T
Y
K
K
K
Frog
Xenopus laevis
Q6GM59
460
50319
C233
S
H
K
K
L
C
Y
C
T
T
K
E
Y
H
F
Zebra Danio
Brachydanio rerio
Q503M4
477
51835
Y245
C
F
Q
S
M
Q
E
Y
H
F
L
L
M
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.4
97.1
80.6
N.A.
26
22.7
N.A.
53.3
28
33.8
26.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
58.3
98.3
87
N.A.
41.6
41.3
N.A.
65.5
45.1
50.7
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
0
N.A.
0
6.6
N.A.
0
13.3
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
93.3
6.6
N.A.
6.6
26.6
N.A.
13.3
33.3
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
0
10
10
0
% A
% Cys:
10
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
10
0
0
10
0
0
0
0
10
% D
% Glu:
10
10
0
10
0
0
20
20
20
20
0
20
10
10
0
% E
% Phe:
0
10
20
0
0
0
0
10
0
10
20
20
0
0
10
% F
% Gly:
20
0
10
10
10
0
0
0
0
10
10
0
0
30
0
% G
% His:
0
10
0
0
10
0
0
0
10
0
0
0
0
10
0
% H
% Ile:
0
10
0
10
0
0
0
0
0
10
0
0
10
0
10
% I
% Lys:
0
0
10
10
0
0
0
0
10
0
10
0
20
10
20
% K
% Leu:
40
0
0
0
10
10
20
10
10
0
20
10
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
10
0
20
0
0
% M
% Asn:
0
0
10
10
10
20
0
0
0
0
0
10
20
10
0
% N
% Pro:
0
0
10
0
0
0
0
0
10
10
0
0
0
20
20
% P
% Gln:
0
10
10
10
20
10
20
0
10
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% R
% Ser:
20
30
10
30
0
10
10
20
10
10
0
0
0
0
10
% S
% Thr:
0
10
0
0
10
10
0
0
10
10
20
0
0
0
10
% T
% Val:
0
0
20
10
20
20
0
10
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
10
0
0
0
30
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _