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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC16A5
All Species:
4.85
Human Site:
S458
Identified Species:
11.85
UniProt:
O15375
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15375
NP_004686.1
505
54994
S458
S
P
E
I
M
C
Q
S
S
R
Q
P
R
P
A
Chimpanzee
Pan troglodytes
XP_511670
417
45399
R375
C
Q
S
S
R
Q
P
R
P
A
G
V
N
K
H
Rhesus Macaque
Macaca mulatta
XP_001092667
486
52927
A442
E
Q
D
I
F
L
E
A
K
D
G
P
G
K
Q
Dog
Lupus familis
XP_540427
467
50455
K423
S
F
C
A
L
Q
K
K
E
R
Q
S
K
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
P57787
470
50355
V428
E
V
T
E
P
E
E
V
A
S
E
E
K
L
H
Rat
Rattus norvegicus
O70461
492
51572
S445
D
S
E
P
M
P
A
S
T
E
E
P
G
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519172
483
51490
C440
L
K
G
T
T
G
G
C
T
A
A
S
L
P
R
Chicken
Gallus gallus
Q90632
542
58161
S467
N
P
S
A
G
G
G
S
D
T
E
E
A
E
S
Frog
Xenopus laevis
Q6GM59
460
50319
C416
S
G
F
S
M
I
F
C
S
I
L
L
G
L
A
Zebra Danio
Brachydanio rerio
Q503M4
477
51835
Y435
F
S
V
A
I
I
R
Y
C
Q
R
N
Q
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.8
90.3
73.6
N.A.
36.4
38.8
N.A.
49.9
33.5
28.1
28.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
80.5
93
80.7
N.A.
54.6
54.8
N.A.
62.1
52.4
46.9
47.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
13.3
26.6
N.A.
0
26.6
N.A.
6.6
13.3
26.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
33.3
46.6
N.A.
26.6
40
N.A.
13.3
33.3
26.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
30
0
0
10
10
10
20
10
0
10
0
30
% A
% Cys:
10
0
10
0
0
10
0
20
10
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
0
0
0
0
10
10
0
0
0
0
0
% D
% Glu:
20
0
20
10
0
10
20
0
10
10
30
20
0
10
0
% E
% Phe:
10
10
10
0
10
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
0
10
20
20
0
0
0
20
0
30
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% H
% Ile:
0
0
0
20
10
20
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
10
10
10
0
0
0
20
30
10
% K
% Leu:
10
0
0
0
10
10
0
0
0
0
10
10
10
20
10
% L
% Met:
0
0
0
0
30
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% N
% Pro:
0
20
0
10
10
10
10
0
10
0
0
30
0
20
0
% P
% Gln:
0
20
0
0
0
20
10
0
0
10
20
0
10
10
10
% Q
% Arg:
0
0
0
0
10
0
10
10
0
20
10
0
10
0
10
% R
% Ser:
30
20
20
20
0
0
0
30
20
10
0
20
0
10
10
% S
% Thr:
0
0
10
10
10
0
0
0
20
10
0
0
0
0
0
% T
% Val:
0
10
10
0
0
0
0
10
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _