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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NVL
All Species:
13.94
Human Site:
S185
Identified Species:
20.44
UniProt:
O15381
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15381
NP_002524.2
856
95051
S185
T
P
S
V
K
K
D
S
F
F
L
D
L
S
C
Chimpanzee
Pan troglodytes
XP_514229
905
100536
S219
T
P
S
G
K
K
D
S
F
F
L
D
L
S
C
Rhesus Macaque
Macaca mulatta
XP_001096627
856
94931
S185
T
P
S
G
K
K
D
S
F
F
L
D
L
S
D
Dog
Lupus familis
XP_537239
955
104441
L258
T
P
A
G
K
M
G
L
T
D
E
K
S
N
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBY8
855
94457
S184
T
P
G
G
K
K
E
S
L
P
L
D
L
S
D
Rat
Rattus norvegicus
P46462
806
89330
V166
R
A
V
E
F
K
V
V
E
T
D
P
S
P
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512479
677
74669
V113
E
V
Y
H
H
L
G
V
V
P
P
R
G
F
L
Chicken
Gallus gallus
Frog
Xenopus laevis
P23787
805
89193
V166
R
A
V
E
F
K
V
V
E
T
D
P
S
P
Y
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
V166
R
A
V
E
F
K
V
V
E
T
D
P
S
P
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
D166
E
F
K
V
V
L
T
D
P
E
P
Y
C
I
V
Honey Bee
Apis mellifera
XP_392923
818
90486
T166
T
T
T
T
T
S
T
T
I
E
S
A
K
K
R
Nematode Worm
Caenorhab. elegans
P54812
810
89622
F168
A
A
M
R
T
V
E
F
K
V
V
E
T
D
P
Sea Urchin
Strong. purpuratus
XP_785648
742
81148
M168
P
K
L
L
L
P
N
M
K
R
K
E
E
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SS94
820
89986
S171
D
N
Y
A
K
L
N
S
S
S
K
K
P
I
G
Baker's Yeast
Sacchar. cerevisiae
Q07844
837
93051
S181
V
K
K
S
K
K
R
S
K
E
G
T
C
K
V
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
D286
S
A
A
E
E
D
R
D
S
K
T
N
A
Q
T
Conservation
Percent
Protein Identity:
100
92.3
97.6
77.2
N.A.
87.8
35.9
N.A.
65.7
N.A.
35.9
35.7
N.A.
33.8
49.2
35.8
48.1
Protein Similarity:
100
93.1
98.5
83.1
N.A.
93.2
54.2
N.A.
72.1
N.A.
53.3
54.2
N.A.
54.2
65.1
54.2
60.5
P-Site Identity:
100
93.3
86.6
20
N.A.
60
6.6
N.A.
0
N.A.
6.6
6.6
N.A.
6.6
6.6
0
6.6
P-Site Similarity:
100
93.3
86.6
33.3
N.A.
66.6
6.6
N.A.
0
N.A.
6.6
6.6
N.A.
6.6
20
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
42.2
22.9
Protein Similarity:
N.A.
N.A.
N.A.
57
61.5
38.1
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
32
13
7
0
0
0
0
0
0
0
7
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
13
% C
% Asp:
7
0
0
0
0
7
19
13
0
7
19
25
0
7
13
% D
% Glu:
13
0
0
25
7
0
13
0
19
19
7
13
7
0
0
% E
% Phe:
0
7
0
0
19
0
0
7
19
19
0
0
0
7
0
% F
% Gly:
0
0
7
25
0
0
13
0
0
0
7
0
7
0
7
% G
% His:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
0
0
7
0
0
0
0
13
0
% I
% Lys:
0
13
13
0
44
50
0
0
19
7
13
13
7
13
0
% K
% Leu:
0
0
7
7
7
19
0
7
7
0
25
0
25
0
7
% L
% Met:
0
0
7
0
0
7
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
13
0
0
0
0
7
0
7
0
% N
% Pro:
7
32
0
0
0
7
0
0
7
13
13
19
7
19
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
19
0
0
7
0
0
13
0
0
7
0
7
0
0
7
% R
% Ser:
7
0
19
7
0
7
0
38
13
7
7
0
25
32
0
% S
% Thr:
38
7
7
7
13
0
13
7
7
19
7
7
7
0
7
% T
% Val:
7
7
19
13
7
7
19
25
7
7
7
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
13
0
0
0
0
0
0
0
0
7
0
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _