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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NVL
All Species:
14.55
Human Site:
S191
Identified Species:
21.33
UniProt:
O15381
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15381
NP_002524.2
856
95051
S191
D
S
F
F
L
D
L
S
C
E
K
S
N
P
K
Chimpanzee
Pan troglodytes
XP_514229
905
100536
S225
D
S
F
F
L
D
L
S
C
E
K
S
N
P
K
Rhesus Macaque
Macaca mulatta
XP_001096627
856
94931
S191
D
S
F
F
L
D
L
S
D
E
K
S
D
P
K
Dog
Lupus familis
XP_537239
955
104441
N264
G
L
T
D
E
K
S
N
H
K
Q
P
G
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBY8
855
94457
S190
E
S
L
P
L
D
L
S
D
D
Q
S
N
S
K
Rat
Rattus norvegicus
P46462
806
89330
P172
V
V
E
T
D
P
S
P
Y
C
I
V
A
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512479
677
74669
F119
G
V
V
P
P
R
G
F
L
L
H
G
P
P
G
Chicken
Gallus gallus
Frog
Xenopus laevis
P23787
805
89193
P172
V
V
E
T
D
P
S
P
Y
C
I
V
A
P
D
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
P172
V
V
E
T
D
P
S
P
Y
C
I
V
A
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
I172
T
D
P
E
P
Y
C
I
V
A
P
E
T
V
I
Honey Bee
Apis mellifera
XP_392923
818
90486
K172
T
T
I
E
S
A
K
K
R
Q
R
D
E
D
A
Nematode Worm
Caenorhab. elegans
P54812
810
89622
D174
E
F
K
V
V
E
T
D
P
A
P
A
C
I
V
Sea Urchin
Strong. purpuratus
XP_785648
742
81148
S174
N
M
K
R
K
E
E
S
A
Q
E
N
S
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SS94
820
89986
I177
N
S
S
S
K
K
P
I
G
S
P
A
E
K
N
Baker's Yeast
Sacchar. cerevisiae
Q07844
837
93051
K187
R
S
K
E
G
T
C
K
V
K
R
Q
K
I
K
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
Q292
R
D
S
K
T
N
A
Q
T
A
E
T
D
A
D
Conservation
Percent
Protein Identity:
100
92.3
97.6
77.2
N.A.
87.8
35.9
N.A.
65.7
N.A.
35.9
35.7
N.A.
33.8
49.2
35.8
48.1
Protein Similarity:
100
93.1
98.5
83.1
N.A.
93.2
54.2
N.A.
72.1
N.A.
53.3
54.2
N.A.
54.2
65.1
54.2
60.5
P-Site Identity:
100
100
86.6
0
N.A.
53.3
6.6
N.A.
6.6
N.A.
6.6
6.6
N.A.
0
0
0
6.6
P-Site Similarity:
100
100
93.3
26.6
N.A.
73.3
6.6
N.A.
6.6
N.A.
6.6
6.6
N.A.
0
20
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
42.2
22.9
Protein Similarity:
N.A.
N.A.
N.A.
57
61.5
38.1
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
7
0
7
19
0
13
19
7
7
% A
% Cys:
0
0
0
0
0
0
13
0
13
19
0
0
7
0
0
% C
% Asp:
19
13
0
7
19
25
0
7
13
7
0
7
13
7
25
% D
% Glu:
13
0
19
19
7
13
7
0
0
19
13
7
13
0
7
% E
% Phe:
0
7
19
19
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
13
0
0
0
7
0
7
0
7
0
0
7
7
0
7
% G
% His:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
13
0
0
19
0
0
13
7
% I
% Lys:
0
0
19
7
13
13
7
13
0
13
19
0
7
7
32
% K
% Leu:
0
7
7
0
25
0
25
0
7
7
0
0
0
0
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
0
0
0
7
0
7
0
0
0
7
19
0
7
% N
% Pro:
0
0
7
13
13
19
7
19
7
0
19
7
7
44
0
% P
% Gln:
0
0
0
0
0
0
0
7
0
13
13
7
0
0
7
% Q
% Arg:
13
0
0
7
0
7
0
0
7
0
13
0
0
0
0
% R
% Ser:
0
38
13
7
7
0
25
32
0
7
0
25
7
19
0
% S
% Thr:
13
7
7
19
7
7
7
0
7
0
0
7
7
0
0
% T
% Val:
19
25
7
7
7
0
0
0
13
0
0
19
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
19
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _