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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NVL
All Species:
16.67
Human Site:
S260
Identified Species:
24.44
UniProt:
O15381
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15381
NP_002524.2
856
95051
S260
R
G
L
E
F
Q
I
S
N
V
K
F
E
D
V
Chimpanzee
Pan troglodytes
XP_514229
905
100536
S294
R
G
L
E
F
Q
I
S
N
V
K
F
E
D
V
Rhesus Macaque
Macaca mulatta
XP_001096627
856
94931
S260
R
G
L
E
F
Q
I
S
N
V
K
F
E
D
V
Dog
Lupus familis
XP_537239
955
104441
S327
K
G
L
E
L
Q
V
S
R
V
K
F
E
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBY8
855
94457
S259
R
S
T
E
L
Q
I
S
N
V
K
F
E
D
V
Rat
Rattus norvegicus
P46462
806
89330
L224
K
E
M
V
E
L
P
L
R
H
P
A
L
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512479
677
74669
A171
L
R
E
L
F
E
Q
A
V
S
S
A
P
C
I
Chicken
Gallus gallus
Frog
Xenopus laevis
P23787
805
89193
L224
K
E
M
V
E
L
P
L
R
H
P
A
L
F
K
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
L224
K
E
M
V
E
L
P
L
R
H
P
A
L
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
P224
V
E
L
P
L
R
H
P
S
L
F
K
A
I
G
Honey Bee
Apis mellifera
XP_392923
818
90486
I225
P
K
I
T
F
S
D
I
G
G
N
D
K
V
L
Nematode Worm
Caenorhab. elegans
P54812
810
89622
E226
A
Q
I
K
E
M
V
E
L
P
L
R
H
P
Q
Sea Urchin
Strong. purpuratus
XP_785648
742
81148
G226
R
S
S
E
S
E
G
G
R
K
G
K
K
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SS94
820
89986
G229
L
E
V
E
G
T
K
G
P
T
F
K
D
F
G
Baker's Yeast
Sacchar. cerevisiae
Q07844
837
93051
G241
T
G
V
E
P
P
R
G
V
L
L
H
G
P
P
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
P396
P
D
L
L
H
P
K
P
T
P
E
D
D
E
E
Conservation
Percent
Protein Identity:
100
92.3
97.6
77.2
N.A.
87.8
35.9
N.A.
65.7
N.A.
35.9
35.7
N.A.
33.8
49.2
35.8
48.1
Protein Similarity:
100
93.1
98.5
83.1
N.A.
93.2
54.2
N.A.
72.1
N.A.
53.3
54.2
N.A.
54.2
65.1
54.2
60.5
P-Site Identity:
100
100
100
73.3
N.A.
80
0
N.A.
6.6
N.A.
0
0
N.A.
6.6
6.6
0
20
P-Site Similarity:
100
100
100
86.6
N.A.
80
13.3
N.A.
26.6
N.A.
13.3
13.3
N.A.
26.6
26.6
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
42.2
22.9
Protein Similarity:
N.A.
N.A.
N.A.
57
61.5
38.1
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
7
0
0
0
25
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
7
0
0
0
0
7
0
0
0
0
13
13
32
0
% D
% Glu:
0
32
7
50
25
13
0
7
0
0
7
0
32
7
7
% E
% Phe:
0
0
0
0
32
0
0
0
0
0
13
32
0
25
0
% F
% Gly:
0
32
0
0
7
0
7
19
7
7
7
0
7
0
13
% G
% His:
0
0
0
0
7
0
7
0
0
19
0
7
7
0
0
% H
% Ile:
0
0
13
0
0
0
25
7
0
0
0
0
0
7
7
% I
% Lys:
25
7
0
7
0
0
13
0
0
7
32
19
13
7
19
% K
% Leu:
13
0
38
13
19
19
0
19
7
13
13
0
19
0
7
% L
% Met:
0
0
19
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
25
0
7
0
0
0
0
% N
% Pro:
13
0
0
7
7
13
19
13
7
13
19
0
7
13
7
% P
% Gln:
0
7
0
0
0
32
7
0
0
0
0
0
0
0
7
% Q
% Arg:
32
7
0
0
0
7
7
0
32
0
0
7
0
0
0
% R
% Ser:
0
13
7
0
7
7
0
32
7
7
7
0
0
0
0
% S
% Thr:
7
0
7
7
0
7
0
0
7
7
0
0
0
0
0
% T
% Val:
7
0
13
19
0
0
13
0
13
32
0
0
0
7
38
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _