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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NVL
All Species:
19.09
Human Site:
S522
Identified Species:
28
UniProt:
O15381
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15381
NP_002524.2
856
95051
S522
R
L
G
T
E
P
T
S
E
T
Q
D
E
L
Q
Chimpanzee
Pan troglodytes
XP_514229
905
100536
S556
R
L
G
T
E
P
T
S
E
T
Q
D
E
L
Q
Rhesus Macaque
Macaca mulatta
XP_001096627
856
94931
S522
S
L
G
T
E
S
T
S
E
T
Q
D
E
L
Q
Dog
Lupus familis
XP_537239
955
104441
S589
R
V
G
T
E
P
A
S
E
T
P
D
E
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBY8
855
94457
S521
R
L
G
A
E
P
T
S
E
T
Q
D
E
L
Q
Rat
Rattus norvegicus
P46462
806
89330
I430
I
R
K
K
M
D
L
I
D
L
E
D
E
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512479
677
74669
M374
L
Q
M
L
C
I
E
M
N
D
F
T
V
A
L
Chicken
Gallus gallus
Frog
Xenopus laevis
P23787
805
89193
I430
I
R
K
K
M
D
L
I
D
L
E
D
E
T
I
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
I430
I
R
K
K
M
D
L
I
D
L
E
D
E
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
I427
I
R
E
K
M
D
L
I
D
L
E
D
D
K
I
Honey Bee
Apis mellifera
XP_392923
818
90486
T492
E
V
T
I
E
P
S
T
S
D
Q
N
V
P
K
Nematode Worm
Caenorhab. elegans
P54812
810
89622
E430
A
A
I
Q
Q
I
R
E
K
M
E
L
I
D
L
Sea Urchin
Strong. purpuratus
XP_785648
742
81148
R429
H
V
L
C
R
K
L
R
L
S
G
D
F
S
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SS94
820
89986
E472
I
L
D
S
R
K
S
E
Q
S
G
D
G
E
D
Baker's Yeast
Sacchar. cerevisiae
Q07844
837
93051
D475
K
N
T
A
N
M
I
D
P
L
P
L
S
V
V
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
A876
T
H
E
L
E
M
S
A
P
D
E
Q
E
R
E
Conservation
Percent
Protein Identity:
100
92.3
97.6
77.2
N.A.
87.8
35.9
N.A.
65.7
N.A.
35.9
35.7
N.A.
33.8
49.2
35.8
48.1
Protein Similarity:
100
93.1
98.5
83.1
N.A.
93.2
54.2
N.A.
72.1
N.A.
53.3
54.2
N.A.
54.2
65.1
54.2
60.5
P-Site Identity:
100
100
86.6
80
N.A.
93.3
13.3
N.A.
0
N.A.
13.3
13.3
N.A.
6.6
20
0
6.6
P-Site Similarity:
100
100
86.6
86.6
N.A.
93.3
26.6
N.A.
0
N.A.
26.6
26.6
N.A.
26.6
53.3
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
42.2
22.9
Protein Similarity:
N.A.
N.A.
N.A.
57
61.5
38.1
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
40
13.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
13
0
0
7
7
0
0
0
0
0
7
0
% A
% Cys:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
25
0
7
25
19
0
69
7
7
7
% D
% Glu:
7
0
13
0
44
0
7
13
32
0
38
0
57
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% F
% Gly:
0
0
32
0
0
0
0
0
0
0
13
0
7
0
0
% G
% His:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
32
0
7
7
0
13
7
25
0
0
0
0
7
0
25
% I
% Lys:
7
0
19
25
0
13
0
0
7
0
0
0
0
7
7
% K
% Leu:
7
32
7
13
0
0
32
0
7
32
0
13
0
32
13
% L
% Met:
0
0
7
0
25
13
0
7
0
7
0
0
0
0
0
% M
% Asn:
0
7
0
0
7
0
0
0
7
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
32
0
0
13
0
13
0
0
7
0
% P
% Gln:
0
7
0
7
7
0
0
0
7
0
32
7
0
0
32
% Q
% Arg:
25
25
0
0
13
0
7
7
0
0
0
0
0
7
0
% R
% Ser:
7
0
0
7
0
7
19
32
7
13
0
0
7
7
0
% S
% Thr:
7
0
13
25
0
0
25
7
0
32
0
7
0
19
0
% T
% Val:
0
19
0
0
0
0
0
0
0
0
0
0
13
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _