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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NVL
All Species:
38.18
Human Site:
S566
Identified Species:
56
UniProt:
O15381
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15381
NP_002524.2
856
95051
S566
A
L
S
S
V
Q
P
S
A
K
R
E
G
F
V
Chimpanzee
Pan troglodytes
XP_514229
905
100536
S600
A
L
S
S
V
Q
P
S
A
K
R
E
G
F
V
Rhesus Macaque
Macaca mulatta
XP_001096627
856
94931
S566
A
L
S
S
V
Q
P
S
A
K
R
E
G
F
V
Dog
Lupus familis
XP_537239
955
104441
S633
A
L
S
S
V
Q
P
S
A
K
R
E
G
F
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBY8
855
94457
S565
A
L
A
E
V
Q
P
S
A
K
R
E
G
F
V
Rat
Rattus norvegicus
P46462
806
89330
T467
N
P
S
A
L
R
E
T
V
V
E
V
P
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512479
677
74669
R411
I
G
A
L
E
D
I
R
E
E
L
T
M
A
I
Chicken
Gallus gallus
Frog
Xenopus laevis
P23787
805
89193
T467
N
P
S
A
L
R
E
T
V
V
E
V
P
Q
V
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
T467
N
P
S
A
L
R
E
T
V
V
E
V
P
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
T464
S
P
S
A
L
R
E
T
V
V
E
V
P
N
T
Honey Bee
Apis mellifera
XP_392923
818
90486
S538
A
L
R
I
I
Q
P
S
A
K
R
E
G
F
A
Nematode Worm
Caenorhab. elegans
P54812
810
89622
S467
A
M
G
K
S
S
P
S
A
L
R
E
A
V
V
Sea Urchin
Strong. purpuratus
XP_785648
742
81148
I466
A
M
A
A
V
N
R
I
P
M
K
S
D
H
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SS94
820
89986
S513
A
V
N
L
V
Q
A
S
L
T
R
E
G
F
S
Baker's Yeast
Sacchar. cerevisiae
Q07844
837
93051
T518
A
L
P
T
I
Q
P
T
A
K
R
E
G
F
A
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
F976
V
D
A
A
R
K
N
F
A
D
S
I
G
A
P
Conservation
Percent
Protein Identity:
100
92.3
97.6
77.2
N.A.
87.8
35.9
N.A.
65.7
N.A.
35.9
35.7
N.A.
33.8
49.2
35.8
48.1
Protein Similarity:
100
93.1
98.5
83.1
N.A.
93.2
54.2
N.A.
72.1
N.A.
53.3
54.2
N.A.
54.2
65.1
54.2
60.5
P-Site Identity:
100
100
100
100
N.A.
86.6
13.3
N.A.
0
N.A.
13.3
6.6
N.A.
6.6
73.3
46.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
40
N.A.
20
N.A.
40
40
N.A.
40
80
53.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
42.2
22.9
Protein Similarity:
N.A.
N.A.
N.A.
57
61.5
38.1
P-Site Identity:
N.A.
N.A.
N.A.
53.3
66.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
86.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
63
0
25
38
0
0
7
0
57
0
0
0
7
13
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
7
0
0
0
7
0
0
7
0
0
% D
% Glu:
0
0
0
7
7
0
25
0
7
7
25
57
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
50
0
% F
% Gly:
0
7
7
0
0
0
0
0
0
0
0
0
57
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
7
0
0
7
13
0
7
7
0
0
0
7
0
0
19
% I
% Lys:
0
0
0
7
0
7
0
0
0
44
7
0
0
0
0
% K
% Leu:
0
44
0
13
25
0
0
0
7
7
7
0
0
0
0
% L
% Met:
0
13
0
0
0
0
0
0
0
7
0
0
7
0
0
% M
% Asn:
19
0
7
0
0
7
7
0
0
0
0
0
0
13
0
% N
% Pro:
0
25
7
0
0
0
50
0
7
0
0
0
25
0
7
% P
% Gln:
0
0
0
0
0
50
0
0
0
0
0
0
0
13
0
% Q
% Arg:
0
0
7
0
7
25
7
7
0
0
57
0
0
0
0
% R
% Ser:
7
0
50
25
7
7
0
50
0
0
7
7
0
0
7
% S
% Thr:
0
0
0
7
0
0
0
32
0
7
0
7
0
0
7
% T
% Val:
7
7
0
0
44
0
0
0
25
25
0
25
0
7
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _