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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NVL
All Species:
22.12
Human Site:
T743
Identified Species:
32.44
UniProt:
O15381
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15381
NP_002524.2
856
95051
T743
R
P
G
R
L
D
K
T
L
F
V
G
L
P
P
Chimpanzee
Pan troglodytes
XP_514229
905
100536
T792
R
P
G
R
L
D
K
T
L
F
V
G
L
P
P
Rhesus Macaque
Macaca mulatta
XP_001096627
856
94931
T743
R
P
G
R
L
D
K
T
L
F
V
G
L
P
P
Dog
Lupus familis
XP_537239
955
104441
T810
R
P
G
R
L
D
K
T
L
F
V
G
L
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBY8
855
94457
T742
R
P
G
R
L
D
K
T
L
F
V
G
L
P
P
Rat
Rattus norvegicus
P46462
806
89330
L642
R
P
G
R
L
D
Q
L
I
Y
I
P
L
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512479
677
74669
D574
V
G
L
P
P
P
A
D
R
F
A
I
L
R
T
Chicken
Gallus gallus
Frog
Xenopus laevis
P23787
805
89193
L642
R
P
G
R
L
D
Q
L
I
Y
I
P
L
P
D
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
L642
R
P
G
R
L
D
Q
L
I
Y
I
P
L
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
L639
R
P
G
R
L
D
Q
L
I
Y
I
P
L
P
D
Honey Bee
Apis mellifera
XP_392923
818
90486
L712
A
V
L
R
P
G
R
L
D
K
I
L
Y
V
D
Nematode Worm
Caenorhab. elegans
P54812
810
89622
L647
R
P
G
R
L
D
Q
L
I
Y
I
P
L
P
D
Sea Urchin
Strong. purpuratus
XP_785648
742
81148
L635
C
V
I
F
F
D
E
L
D
A
L
C
P
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SS94
820
89986
L689
R
P
G
R
F
G
N
L
L
Y
V
P
L
P
N
Baker's Yeast
Sacchar. cerevisiae
Q07844
837
93051
S695
R
P
G
R
L
D
K
S
L
F
I
E
L
P
N
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
M1158
R
P
G
R
F
D
K
M
L
Y
L
G
V
S
D
Conservation
Percent
Protein Identity:
100
92.3
97.6
77.2
N.A.
87.8
35.9
N.A.
65.7
N.A.
35.9
35.7
N.A.
33.8
49.2
35.8
48.1
Protein Similarity:
100
93.1
98.5
83.1
N.A.
93.2
54.2
N.A.
72.1
N.A.
53.3
54.2
N.A.
54.2
65.1
54.2
60.5
P-Site Identity:
100
100
100
100
N.A.
100
53.3
N.A.
13.3
N.A.
53.3
53.3
N.A.
53.3
6.6
53.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
80
N.A.
13.3
N.A.
80
80
N.A.
80
20
80
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
42.2
22.9
Protein Similarity:
N.A.
N.A.
N.A.
57
61.5
38.1
P-Site Identity:
N.A.
N.A.
N.A.
53.3
73.3
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
60
86.6
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
7
0
0
7
7
0
0
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
0
0
0
0
82
0
7
13
0
0
0
0
0
44
% D
% Glu:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
0
% E
% Phe:
0
0
0
7
19
0
0
0
0
44
0
0
0
0
0
% F
% Gly:
0
7
82
0
0
13
0
0
0
0
0
38
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
32
0
44
7
0
0
0
% I
% Lys:
0
0
0
0
0
0
44
0
0
7
0
0
0
0
0
% K
% Leu:
0
0
13
0
69
0
0
50
50
0
13
7
82
0
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
13
% N
% Pro:
0
82
0
7
13
7
0
0
0
0
0
38
7
75
32
% P
% Gln:
0
0
0
0
0
0
32
0
0
0
0
0
0
0
0
% Q
% Arg:
82
0
0
88
0
0
7
0
7
0
0
0
0
13
7
% R
% Ser:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% S
% Thr:
0
0
0
0
0
0
0
32
0
0
0
0
0
0
7
% T
% Val:
7
13
0
0
0
0
0
0
0
0
38
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
44
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _