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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BCAT2 All Species: 20.3
Human Site: T317 Identified Species: 34.36
UniProt: O15382 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.46
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15382 NP_001181.2 392 44288 T317 E F R V V E R T I T M K Q L L
Chimpanzee Pan troglodytes XP_001171838 392 44145 T317 E F R V V E R T I T M K Q L L
Rhesus Macaque Macaca mulatta XP_001114272 392 44184 T317 E F R V V E R T I T M K Q L L
Dog Lupus familis XP_541509 393 44485 K318 E F R V V E R K V T M K E L L
Cat Felis silvestris
Mouse Mus musculus O35855 393 44109 K318 E F R V A E R K V T M K E L K
Rat Rattus norvegicus O35854 393 44257 K318 E F R V A E R K V T M K E L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505701 458 51606 Y284 E F K V S E R Y L T M N D L I
Chicken Gallus gallus XP_416424 386 43007 Y310 E F K V S E R Y I T M S D L T
Frog Xenopus laevis NP_001106354 448 50156 S322 E F K V S E R S V T M S E V I
Zebra Danio Brachydanio rerio NP_001002676 415 46469 R339 E F K V T E R R V F M K E L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54688 415 47323 R332 G E Y K V T E R T L N M E E V
Sea Urchin Strong. purpuratus XP_788267 391 44250 R328 D F K V T E R R I T M A E F Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FYA6 415 45563 V345 F K V E E R N V T V D E L V E
Baker's Yeast Sacchar. cerevisiae P47176 376 41606 S291 E P S E W T I S E R Y F T I G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 96.6 86.2 N.A. 83.4 81.1 N.A. 49.1 57.4 54 57.3 N.A. N.A. N.A. 45.5 50
Protein Similarity: 100 98.2 98.2 93.6 N.A. 90.8 89.8 N.A. 63 72.9 72 70.1 N.A. N.A. N.A. 65.5 68.3
P-Site Identity: 100 100 100 80 N.A. 66.6 66.6 N.A. 53.3 60 46.6 60 N.A. N.A. N.A. 6.6 46.6
P-Site Similarity: 100 100 100 93.3 N.A. 80 80 N.A. 73.3 66.6 86.6 80 N.A. N.A. N.A. 20 66.6
Percent
Protein Identity: N.A. N.A. N.A. 30.6 44.1 N.A.
Protein Similarity: N.A. N.A. N.A. 50.3 58.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 15 0 0 0 0 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 0 8 0 15 0 0 % D
% Glu: 79 8 0 15 8 79 8 0 8 0 0 8 50 8 8 % E
% Phe: 8 79 0 0 0 0 0 0 0 8 0 8 0 8 0 % F
% Gly: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 36 0 0 0 0 8 15 % I
% Lys: 0 8 36 8 0 0 0 22 0 0 0 50 0 0 15 % K
% Leu: 0 0 0 0 0 0 0 0 8 8 0 0 8 65 36 % L
% Met: 0 0 0 0 0 0 0 0 0 0 79 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 8 8 0 0 0 % N
% Pro: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 22 0 8 % Q
% Arg: 0 0 43 0 0 8 79 22 0 8 0 0 0 0 0 % R
% Ser: 0 0 8 0 22 0 0 15 0 0 0 15 0 0 0 % S
% Thr: 0 0 0 0 15 15 0 22 15 72 0 0 8 0 8 % T
% Val: 0 0 8 79 36 0 0 8 36 8 0 0 0 15 8 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 15 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _