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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BCAT2 All Species: 31.52
Human Site: T42 Identified Species: 53.33
UniProt: O15382 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15382 NP_001181.2 392 44288 T42 A D L Q L E M T Q K P H K K P
Chimpanzee Pan troglodytes XP_001171838 392 44145 T42 A D L Q L E M T Q K P H K K P
Rhesus Macaque Macaca mulatta XP_001114272 392 44184 T42 A D L Q L E M T Q K P H K K P
Dog Lupus familis XP_541509 393 44485 T42 A D L Q L E M T K E P H Q K P
Cat Felis silvestris
Mouse Mus musculus O35855 393 44109 T42 A D L Q I Q M T K E P Q K K P
Rat Rattus norvegicus O35854 393 44257 T42 A D L Q V Q V T R E P Q K K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505701 458 51606 T33 V F T D H M L T I E W S S D S
Chicken Gallus gallus XP_416424 386 43007 A35 S D L I I T P A T T L K E K P
Frog Xenopus laevis NP_001106354 448 50156 N47 S D L Q I E L N K H P K E K T
Zebra Danio Brachydanio rerio NP_001002676 415 46469 S64 A D L T I E K S S V L K P K P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54688 415 47323 H36 T V P R E E I H K E Y D R K K
Sea Urchin Strong. purpuratus XP_788267 391 44250 S53 S E V Q I E H S K V L K P K P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FYA6 415 45563 S61 N F I V S E V S R N R R C D A
Baker's Yeast Sacchar. cerevisiae P47176 376 41606 T40 S F T D H M L T A E W T A E K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 96.6 86.2 N.A. 83.4 81.1 N.A. 49.1 57.4 54 57.3 N.A. N.A. N.A. 45.5 50
Protein Similarity: 100 98.2 98.2 93.6 N.A. 90.8 89.8 N.A. 63 72.9 72 70.1 N.A. N.A. N.A. 65.5 68.3
P-Site Identity: 100 100 100 80 N.A. 66.6 60 N.A. 6.6 26.6 40 40 N.A. N.A. N.A. 13.3 26.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 20 46.6 73.3 53.3 N.A. N.A. N.A. 46.6 66.6
Percent
Protein Identity: N.A. N.A. N.A. 30.6 44.1 N.A.
Protein Similarity: N.A. N.A. N.A. 50.3 58.6 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 0 0 0 0 0 0 8 8 0 0 0 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 65 0 15 0 0 0 0 0 0 0 8 0 15 0 % D
% Glu: 0 8 0 0 8 65 0 0 0 43 0 0 15 8 0 % E
% Phe: 0 22 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 15 0 8 8 0 8 0 29 0 0 0 % H
% Ile: 0 0 8 8 36 0 8 0 8 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 36 22 0 29 36 79 15 % K
% Leu: 0 0 65 0 29 0 22 0 0 0 22 0 0 0 0 % L
% Met: 0 0 0 0 0 15 36 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % N
% Pro: 0 0 8 0 0 0 8 0 0 0 50 0 15 0 65 % P
% Gln: 0 0 0 58 0 15 0 0 22 0 0 15 8 0 0 % Q
% Arg: 0 0 0 8 0 0 0 0 15 0 8 8 8 0 0 % R
% Ser: 29 0 0 0 8 0 0 22 8 0 0 8 8 0 8 % S
% Thr: 8 0 15 8 0 8 0 58 8 8 0 8 0 0 8 % T
% Val: 8 8 8 8 8 0 15 0 0 15 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _