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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BCAT2 All Species: 19.7
Human Site: Y228 Identified Species: 33.33
UniProt: O15382 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15382 NP_001181.2 392 44288 Y228 W V G G V G N Y K L G G N Y G
Chimpanzee Pan troglodytes XP_001171838 392 44145 T228 L V G G V G T T V L G G N Y G
Rhesus Macaque Macaca mulatta XP_001114272 392 44184 Y228 W V G G V G N Y K L G G N Y G
Dog Lupus familis XP_541509 393 44485 Y229 W V G G V G D Y K L G G N Y G
Cat Felis silvestris
Mouse Mus musculus O35855 393 44109 C229 W I G G V G D C K L G G N Y G
Rat Rattus norvegicus O35854 393 44257 C229 W I G G V G D C K L G G N Y G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505701 458 51606 C195 W K G G T G D C K M G G N Y G
Chicken Gallus gallus XP_416424 386 43007 C221 W K G G T G D C K L G G N Y G
Frog Xenopus laevis NP_001106354 448 50156 C233 W I G G V G N C K L G G N Y G
Zebra Danio Brachydanio rerio NP_001002676 415 46469 Y250 W R G G V G E Y K M G G N Y G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54688 415 47323 Y243 F P G G V G A Y K M G C N Y A
Sea Urchin Strong. purpuratus XP_788267 391 44250 A239 W H G G V G Y A K M G S N Y A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FYA6 415 45563 V260 T P G G T G G V K T I G N Y A
Baker's Yeast Sacchar. cerevisiae P47176 376 41606 K201 W P G G C G D K K L G A N Y A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 96.6 86.2 N.A. 83.4 81.1 N.A. 49.1 57.4 54 57.3 N.A. N.A. N.A. 45.5 50
Protein Similarity: 100 98.2 98.2 93.6 N.A. 90.8 89.8 N.A. 63 72.9 72 70.1 N.A. N.A. N.A. 65.5 68.3
P-Site Identity: 100 73.3 100 93.3 N.A. 80 80 N.A. 66.6 73.3 86.6 80 N.A. N.A. N.A. 60 60
P-Site Similarity: 100 73.3 100 100 N.A. 93.3 93.3 N.A. 80 80 93.3 86.6 N.A. N.A. N.A. 73.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. 30.6 44.1 N.A.
Protein Similarity: N.A. N.A. N.A. 50.3 58.6 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 60 N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 8 0 0 0 8 0 0 29 % A
% Cys: 0 0 0 0 8 0 0 36 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 0 0 43 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 100 100 0 100 8 0 0 0 93 79 0 0 72 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 22 0 0 0 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 0 15 0 0 0 0 0 8 93 0 0 0 0 0 0 % K
% Leu: 8 0 0 0 0 0 0 0 0 65 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 29 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 22 0 0 0 0 0 100 0 0 % N
% Pro: 0 22 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % S
% Thr: 8 0 0 0 22 0 8 8 0 8 0 0 0 0 0 % T
% Val: 0 29 0 0 72 0 0 8 8 0 0 0 0 0 0 % V
% Trp: 79 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 36 0 0 0 0 0 100 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _