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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BCAT2 All Species: 46.06
Human Site: Y256 Identified Species: 77.95
UniProt: O15382 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15382 NP_001181.2 392 44288 Y256 C E Q V L W L Y G P D H Q L T
Chimpanzee Pan troglodytes XP_001171838 392 44145 Y256 C E Q V L W L Y G P D H Q L T
Rhesus Macaque Macaca mulatta XP_001114272 392 44184 Y256 C E Q V L W L Y G P D H Q L T
Dog Lupus familis XP_541509 393 44485 Y257 C E Q V L W L Y G P D H Q L T
Cat Felis silvestris
Mouse Mus musculus O35855 393 44109 Y257 C E Q V L W L Y G P D H Q L T
Rat Rattus norvegicus O35854 393 44257 Y257 C E Q V L W L Y G P D H Q L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505701 458 51606 Y223 C Q Q V L W L Y G D D E Q I T
Chicken Gallus gallus XP_416424 386 43007 Y249 C Q Q V L W L Y G E D H Q I T
Frog Xenopus laevis NP_001106354 448 50156 Y261 C Q Q V L W L Y G D D H K V T
Zebra Danio Brachydanio rerio NP_001002676 415 46469 Y278 C Q Q V L W L Y G E S E E I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54688 415 47323 Y271 C Q Q V L W L Y G E N E D L T
Sea Urchin Strong. purpuratus XP_788267 391 44250 Y267 C Q Q I L W L Y E E E H Y L T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FYA6 415 45563 V284 K A K G Y S D V L Y L D C L H
Baker's Yeast Sacchar. cerevisiae P47176 376 41606 G230 Q Q N L W L F G P N N N I T E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 96.6 86.2 N.A. 83.4 81.1 N.A. 49.1 57.4 54 57.3 N.A. N.A. N.A. 45.5 50
Protein Similarity: 100 98.2 98.2 93.6 N.A. 90.8 89.8 N.A. 63 72.9 72 70.1 N.A. N.A. N.A. 65.5 68.3
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 73.3 80 73.3 60 N.A. N.A. N.A. 66.6 60
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 86.6 93.3 93.3 80 N.A. N.A. N.A. 80 80
Percent
Protein Identity: N.A. N.A. N.A. 30.6 44.1 N.A.
Protein Similarity: N.A. N.A. N.A. 50.3 58.6 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 86 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 15 65 8 8 0 0 % D
% Glu: 0 43 0 0 0 0 0 0 8 29 8 22 8 0 8 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 0 8 79 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 65 0 0 8 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 0 0 8 22 0 % I
% Lys: 8 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 0 0 0 8 86 8 86 0 8 0 8 0 0 65 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 8 15 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 8 43 0 0 0 0 0 % P
% Gln: 8 50 86 0 0 0 0 0 0 0 0 0 58 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 86 % T
% Val: 0 0 0 79 0 0 0 8 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 8 86 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 86 0 8 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _