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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BCAT2 All Species: 16.67
Human Site: Y27 Identified Species: 28.21
UniProt: O15382 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15382 NP_001181.2 392 44288 Y27 L L C G P R R Y A S S S F K A
Chimpanzee Pan troglodytes XP_001171838 392 44145 Y27 L L C G P R R Y A S S S F K A
Rhesus Macaque Macaca mulatta XP_001114272 392 44184 Y27 L L C G P R R Y A S S N F K A
Dog Lupus familis XP_541509 393 44485 Y27 L L C G P R R Y A S S N F K A
Cat Felis silvestris
Mouse Mus musculus O35855 393 44109 C27 L L C G S K R C V S S I F K A
Rat Rattus norvegicus O35854 393 44257 C27 R L C V P G R C V S S N F K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505701 458 51606 P18 V L K E K P D P E S L V F G T
Chicken Gallus gallus XP_416424 386 43007 Y20 C S E E A T K Y V T E S F K A
Frog Xenopus laevis NP_001106354 448 50156 A32 W P S I L C R A A S T S F K A
Zebra Danio Brachydanio rerio NP_001002676 415 46469 L49 C L F L S L C L S D C L C Q A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54688 415 47323 M21 N L V G S R L M A S A A R L E
Sea Urchin Strong. purpuratus XP_788267 391 44250 S38 C A V R C V H S N H D S F K Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FYA6 415 45563 H46 S S S L R I R H C P S P I S S
Baker's Yeast Sacchar. cerevisiae P47176 376 41606 N25 H A S K P K P N S E L V F G K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 96.6 86.2 N.A. 83.4 81.1 N.A. 49.1 57.4 54 57.3 N.A. N.A. N.A. 45.5 50
Protein Similarity: 100 98.2 98.2 93.6 N.A. 90.8 89.8 N.A. 63 72.9 72 70.1 N.A. N.A. N.A. 65.5 68.3
P-Site Identity: 100 100 93.3 93.3 N.A. 66.6 60 N.A. 20 33.3 46.6 13.3 N.A. N.A. N.A. 33.3 20
P-Site Similarity: 100 100 100 100 N.A. 73.3 66.6 N.A. 26.6 46.6 53.3 26.6 N.A. N.A. N.A. 46.6 20
Percent
Protein Identity: N.A. N.A. N.A. 30.6 44.1 N.A.
Protein Similarity: N.A. N.A. N.A. 50.3 58.6 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 0 8 0 0 8 43 0 8 8 0 0 65 % A
% Cys: 22 0 43 0 8 8 8 15 8 0 8 0 8 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 8 8 0 0 0 0 % D
% Glu: 0 0 8 15 0 0 0 0 8 8 8 0 0 0 8 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 79 0 0 % F
% Gly: 0 0 0 43 0 8 0 0 0 0 0 0 0 15 0 % G
% His: 8 0 0 0 0 0 8 8 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 8 0 0 0 0 0 8 8 0 0 % I
% Lys: 0 0 8 8 8 15 8 0 0 0 0 0 0 65 8 % K
% Leu: 36 65 0 15 8 8 8 8 0 0 15 8 0 8 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 8 8 0 0 22 0 0 0 % N
% Pro: 0 8 0 0 43 8 8 8 0 8 0 8 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 8 0 0 8 8 36 58 0 0 0 0 0 8 0 0 % R
% Ser: 8 15 22 0 22 0 0 8 15 65 50 36 0 8 8 % S
% Thr: 0 0 0 0 0 8 0 0 0 8 8 0 0 0 8 % T
% Val: 8 0 15 8 0 8 0 0 22 0 0 15 0 0 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 36 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _