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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BCAT2 All Species: 36.97
Human Site: Y352 Identified Species: 62.56
UniProt: O15382 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15382 NP_001181.2 392 44288 Y352 C P V H R I L Y K D R N L H I
Chimpanzee Pan troglodytes XP_001171838 392 44145 Y352 C P V H R I L Y K D R N L H I
Rhesus Macaque Macaca mulatta XP_001114272 392 44184 Y352 C P V H R I L Y K D K N L H I
Dog Lupus familis XP_541509 393 44485 Y353 C P V H Q I L Y Q G K H L R I
Cat Felis silvestris
Mouse Mus musculus O35855 393 44109 Y353 C P V H Q I L Y E G K Q L H I
Rat Rattus norvegicus O35854 393 44257 Y353 C P V H Q I L Y E G K Q L H I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505701 458 51606 Y319 C P V S E I L Y R G Q T L H I
Chicken Gallus gallus XP_416424 386 43007 Y345 C P I S K I L Y K G K H L H I
Frog Xenopus laevis NP_001106354 448 50156 Y357 C P I K S I L Y Q G T D Y P L
Zebra Danio Brachydanio rerio NP_001002676 415 46469 Y374 C P V G S L L Y K G Q T Y Q I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54688 415 47323 Y368 S P V G K I L Y H N K V T D E
Sea Urchin Strong. purpuratus XP_788267 391 44250 K360 C V V C P I G K V L F K G D M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FYA6 415 45563 Y380 Y K S Q R F S Y G E D G F G T
Baker's Yeast Sacchar. cerevisiae P47176 376 41606 W329 S P I K E I G W K G E Q I N I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 96.6 86.2 N.A. 83.4 81.1 N.A. 49.1 57.4 54 57.3 N.A. N.A. N.A. 45.5 50
Protein Similarity: 100 98.2 98.2 93.6 N.A. 90.8 89.8 N.A. 63 72.9 72 70.1 N.A. N.A. N.A. 65.5 68.3
P-Site Identity: 100 100 93.3 60 N.A. 66.6 66.6 N.A. 60 60 33.3 46.6 N.A. N.A. N.A. 33.3 20
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. 73.3 86.6 60 60 N.A. N.A. N.A. 53.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 30.6 44.1 N.A.
Protein Similarity: N.A. N.A. N.A. 50.3 58.6 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 79 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 22 8 8 0 15 0 % D
% Glu: 0 0 0 0 15 0 0 0 15 8 8 0 0 0 8 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 8 0 8 0 0 % F
% Gly: 0 0 0 15 0 0 15 0 8 58 0 8 8 8 0 % G
% His: 0 0 0 43 0 0 0 0 8 0 0 15 0 50 0 % H
% Ile: 0 0 22 0 0 86 0 0 0 0 0 0 8 0 72 % I
% Lys: 0 8 0 15 15 0 0 8 43 0 43 8 0 0 0 % K
% Leu: 0 0 0 0 0 8 79 0 0 8 0 0 58 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 0 22 0 8 0 % N
% Pro: 0 86 0 0 8 0 0 0 0 0 0 0 0 8 0 % P
% Gln: 0 0 0 8 22 0 0 0 15 0 15 22 0 8 0 % Q
% Arg: 0 0 0 0 29 0 0 0 8 0 15 0 0 8 0 % R
% Ser: 15 0 8 15 15 0 8 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 8 15 8 0 8 % T
% Val: 0 8 72 0 0 0 0 0 8 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 86 0 0 0 0 15 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _