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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BCAT2 All Species: 29.7
Human Site: Y381 Identified Species: 50.26
UniProt: O15382 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15382 NP_001181.2 392 44288 Y381 K E L K E I Q Y G I R A H E W
Chimpanzee Pan troglodytes XP_001171838 392 44145 Y381 K E L K E I Q Y G I R A H E W
Rhesus Macaque Macaca mulatta XP_001114272 392 44184 Y381 K E L K E I Q Y G I R A H E W
Dog Lupus familis XP_541509 393 44485 Y382 K E L K E I Q Y G T R A H D W
Cat Felis silvestris
Mouse Mus musculus O35855 393 44109 Y382 K E L K A I Q Y G A S A H D W
Rat Rattus norvegicus O35854 393 44257 Y382 K E L K A I Q Y G T S A H D W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505701 458 51606 G365 G Q V A E M E G G A S M E E K
Chicken Gallus gallus XP_416424 386 43007 Y374 N K L T D I Q Y G R E D S D W
Frog Xenopus laevis NP_001106354 448 50156 V386 K E L T D I Q V L L L K A V S
Zebra Danio Brachydanio rerio NP_001002676 415 46469 Y403 K E L T D I Q Y G R L Q R D W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54688 415 47323 Y403 N T I N D I Q Y G R I I K D G
Sea Urchin Strong. purpuratus XP_788267 391 44250 Y384 A E L C K R F Y N T L M D I Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FYA6 415 45563 D406 L Q M G L S E D N M N W T V Q
Baker's Yeast Sacchar. cerevisiae P47176 376 41606 N356 K E V A Q W I N G I Q Y G E T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 96.6 86.2 N.A. 83.4 81.1 N.A. 49.1 57.4 54 57.3 N.A. N.A. N.A. 45.5 50
Protein Similarity: 100 98.2 98.2 93.6 N.A. 90.8 89.8 N.A. 63 72.9 72 70.1 N.A. N.A. N.A. 65.5 68.3
P-Site Identity: 100 100 100 86.6 N.A. 73.3 73.3 N.A. 20 40 33.3 53.3 N.A. N.A. N.A. 26.6 20
P-Site Similarity: 100 100 100 93.3 N.A. 80 80 N.A. 46.6 60 46.6 66.6 N.A. N.A. N.A. 46.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. 30.6 44.1 N.A.
Protein Similarity: N.A. N.A. N.A. 50.3 58.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 15 15 0 0 0 0 15 0 43 8 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 29 0 0 8 0 0 0 8 8 43 0 % D
% Glu: 0 72 0 0 36 0 15 0 0 0 8 0 8 36 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 8 0 0 0 8 79 0 0 0 8 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 43 0 0 % H
% Ile: 0 0 8 0 0 72 8 0 0 29 8 8 0 8 0 % I
% Lys: 65 8 0 43 8 0 0 0 0 0 0 8 8 0 8 % K
% Leu: 8 0 72 0 8 0 0 0 8 8 22 0 0 0 0 % L
% Met: 0 0 8 0 0 8 0 0 0 8 0 15 0 0 0 % M
% Asn: 15 0 0 8 0 0 0 8 15 0 8 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 15 0 0 8 0 72 0 0 0 8 8 0 0 15 % Q
% Arg: 0 0 0 0 0 8 0 0 0 22 29 0 8 0 0 % R
% Ser: 0 0 0 0 0 8 0 0 0 0 22 0 8 0 8 % S
% Thr: 0 8 0 22 0 0 0 0 0 22 0 0 8 0 8 % T
% Val: 0 0 15 0 0 0 0 8 0 0 0 0 0 15 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 58 % W
% Tyr: 0 0 0 0 0 0 0 72 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _