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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCAT2
All Species:
29.7
Human Site:
Y381
Identified Species:
50.26
UniProt:
O15382
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15382
NP_001181.2
392
44288
Y381
K
E
L
K
E
I
Q
Y
G
I
R
A
H
E
W
Chimpanzee
Pan troglodytes
XP_001171838
392
44145
Y381
K
E
L
K
E
I
Q
Y
G
I
R
A
H
E
W
Rhesus Macaque
Macaca mulatta
XP_001114272
392
44184
Y381
K
E
L
K
E
I
Q
Y
G
I
R
A
H
E
W
Dog
Lupus familis
XP_541509
393
44485
Y382
K
E
L
K
E
I
Q
Y
G
T
R
A
H
D
W
Cat
Felis silvestris
Mouse
Mus musculus
O35855
393
44109
Y382
K
E
L
K
A
I
Q
Y
G
A
S
A
H
D
W
Rat
Rattus norvegicus
O35854
393
44257
Y382
K
E
L
K
A
I
Q
Y
G
T
S
A
H
D
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505701
458
51606
G365
G
Q
V
A
E
M
E
G
G
A
S
M
E
E
K
Chicken
Gallus gallus
XP_416424
386
43007
Y374
N
K
L
T
D
I
Q
Y
G
R
E
D
S
D
W
Frog
Xenopus laevis
NP_001106354
448
50156
V386
K
E
L
T
D
I
Q
V
L
L
L
K
A
V
S
Zebra Danio
Brachydanio rerio
NP_001002676
415
46469
Y403
K
E
L
T
D
I
Q
Y
G
R
L
Q
R
D
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P54688
415
47323
Y403
N
T
I
N
D
I
Q
Y
G
R
I
I
K
D
G
Sea Urchin
Strong. purpuratus
XP_788267
391
44250
Y384
A
E
L
C
K
R
F
Y
N
T
L
M
D
I
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FYA6
415
45563
D406
L
Q
M
G
L
S
E
D
N
M
N
W
T
V
Q
Baker's Yeast
Sacchar. cerevisiae
P47176
376
41606
N356
K
E
V
A
Q
W
I
N
G
I
Q
Y
G
E
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
96.6
86.2
N.A.
83.4
81.1
N.A.
49.1
57.4
54
57.3
N.A.
N.A.
N.A.
45.5
50
Protein Similarity:
100
98.2
98.2
93.6
N.A.
90.8
89.8
N.A.
63
72.9
72
70.1
N.A.
N.A.
N.A.
65.5
68.3
P-Site Identity:
100
100
100
86.6
N.A.
73.3
73.3
N.A.
20
40
33.3
53.3
N.A.
N.A.
N.A.
26.6
20
P-Site Similarity:
100
100
100
93.3
N.A.
80
80
N.A.
46.6
60
46.6
66.6
N.A.
N.A.
N.A.
46.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
44.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.3
58.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
15
15
0
0
0
0
15
0
43
8
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
29
0
0
8
0
0
0
8
8
43
0
% D
% Glu:
0
72
0
0
36
0
15
0
0
0
8
0
8
36
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
8
0
0
0
8
79
0
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
43
0
0
% H
% Ile:
0
0
8
0
0
72
8
0
0
29
8
8
0
8
0
% I
% Lys:
65
8
0
43
8
0
0
0
0
0
0
8
8
0
8
% K
% Leu:
8
0
72
0
8
0
0
0
8
8
22
0
0
0
0
% L
% Met:
0
0
8
0
0
8
0
0
0
8
0
15
0
0
0
% M
% Asn:
15
0
0
8
0
0
0
8
15
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
15
0
0
8
0
72
0
0
0
8
8
0
0
15
% Q
% Arg:
0
0
0
0
0
8
0
0
0
22
29
0
8
0
0
% R
% Ser:
0
0
0
0
0
8
0
0
0
0
22
0
8
0
8
% S
% Thr:
0
8
0
22
0
0
0
0
0
22
0
0
8
0
8
% T
% Val:
0
0
15
0
0
0
0
8
0
0
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
58
% W
% Tyr:
0
0
0
0
0
0
0
72
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _