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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIGLEC5
All Species:
6.36
Human Site:
S530
Identified Species:
23.33
UniProt:
O15389
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15389
NP_003821.1
551
60715
S530
L
S
F
S
E
M
K
S
R
E
P
K
D
Q
E
Chimpanzee
Pan troglodytes
Q64JA4
387
42507
S367
L
I
I
L
R
V
K
S
H
R
R
K
A
A
K
Rhesus Macaque
Macaca mulatta
NP_001103356
551
60658
S530
L
S
F
S
E
M
K
S
R
E
P
K
D
Q
E
Dog
Lupus familis
XP_533599
629
69179
L608
F
S
F
H
E
M
K
L
R
E
P
Q
D
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q920G3
569
61457
P548
L
S
F
Q
G
P
M
P
P
K
P
Q
N
T
E
Rat
Rattus norvegicus
P07722
626
69334
G588
R
R
L
L
G
L
R
G
E
P
P
E
L
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518834
575
63465
K555
S
L
K
F
L
G
R
K
A
R
E
V
R
L
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.7
86.9
55.3
N.A.
46.5
25.5
N.A.
38.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
49.7
90.7
65.5
N.A.
60.6
41.3
N.A.
55.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
100
66.6
N.A.
33.3
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
100
80
N.A.
53.3
26.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
15
0
0
0
15
15
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
43
15
0
% D
% Glu:
0
0
0
0
43
0
0
0
15
43
15
15
0
15
58
% E
% Phe:
15
0
58
15
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
29
15
0
15
0
0
0
0
0
0
0
% G
% His:
0
0
0
15
0
0
0
0
15
0
0
0
0
0
0
% H
% Ile:
0
15
15
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
15
0
0
0
58
15
0
15
0
43
0
0
15
% K
% Leu:
58
15
15
29
15
15
0
15
0
0
0
0
15
15
15
% L
% Met:
0
0
0
0
0
43
15
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% N
% Pro:
0
0
0
0
0
15
0
15
15
15
72
0
0
0
0
% P
% Gln:
0
0
0
15
0
0
0
0
0
0
0
29
0
29
0
% Q
% Arg:
15
15
0
0
15
0
29
0
43
29
15
0
15
0
0
% R
% Ser:
15
58
0
29
0
0
0
43
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% T
% Val:
0
0
0
0
0
15
0
0
0
0
0
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _