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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YY2
All Species:
30
Human Site:
Y213
Identified Species:
60
UniProt:
O15391
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15391
NP_996806.2
372
41347
Y213
N
P
P
D
Y
S
E
Y
L
K
G
K
K
L
P
Chimpanzee
Pan troglodytes
A2T759
682
76399
T370
N
L
I
K
H
H
R
T
H
T
G
E
K
P
F
Rhesus Macaque
Macaca mulatta
XP_001087143
374
41643
Y215
N
P
P
D
Y
S
E
Y
L
K
G
K
K
L
P
Dog
Lupus familis
XP_548891
812
90519
Y360
S
A
P
D
Y
S
E
Y
M
T
G
K
K
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3TTC2
378
42012
Y219
S
P
P
D
Y
S
E
Y
M
T
G
K
K
F
P
Rat
Rattus norvegicus
P0C6P6
376
41786
Y217
S
T
P
D
Y
S
E
Y
M
T
G
K
K
F
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512875
214
24248
K74
G
I
D
L
S
D
P
K
Q
L
A
E
F
A
R
Chicken
Gallus gallus
NP_001026381
420
45149
Y260
S
P
P
D
Y
S
E
Y
M
T
G
K
K
L
P
Frog
Xenopus laevis
P18725
445
49512
V232
H
S
H
K
N
G
G
V
L
P
R
E
K
P
F
Zebra Danio
Brachydanio rerio
NP_997782
357
39814
Y197
S
P
P
D
Y
S
E
Y
M
T
G
K
K
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8ST83
520
58205
G312
S
S
V
P
F
R
I
G
L
H
E
G
Q
V
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790188
400
44606
Y231
E
P
P
D
Y
S
E
Y
L
T
G
K
K
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.5
89
29.9
N.A.
54.7
57.1
N.A.
42.4
53
20.8
57.7
N.A.
30.1
N.A.
N.A.
46.2
Protein Similarity:
100
31.3
93.8
37.4
N.A.
70.3
72.3
N.A.
51.3
66.9
32.8
72.3
N.A.
43.8
N.A.
N.A.
61
P-Site Identity:
100
20
100
73.3
N.A.
73.3
66.6
N.A.
0
80
13.3
80
N.A.
6.6
N.A.
N.A.
86.6
P-Site Similarity:
100
33.3
100
86.6
N.A.
86.6
80
N.A.
6.6
93.3
26.6
93.3
N.A.
33.3
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
9
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
67
0
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
67
0
0
0
9
25
0
0
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
9
17
17
% F
% Gly:
9
0
0
0
0
9
9
9
0
0
75
9
0
0
0
% G
% His:
9
0
9
0
9
9
0
0
9
9
0
0
0
0
0
% H
% Ile:
0
9
9
0
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
17
0
0
0
9
0
17
0
67
84
0
0
% K
% Leu:
0
9
0
9
0
0
0
0
42
9
0
0
0
50
0
% L
% Met:
0
0
0
0
0
0
0
0
42
0
0
0
0
0
0
% M
% Asn:
25
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
50
67
9
0
0
9
0
0
9
0
0
0
17
67
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% Q
% Arg:
0
0
0
0
0
9
9
0
0
0
9
0
0
0
9
% R
% Ser:
50
17
0
0
9
67
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
9
0
0
0
0
0
9
0
59
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
9
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
67
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _