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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BIRC5
All Species:
26.97
Human Site:
T21
Identified Species:
65.93
UniProt:
O15392
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15392
NP_001012270.1
142
16390
T21
L
K
D
H
R
I
S
T
F
K
N
W
P
F
L
Chimpanzee
Pan troglodytes
XP_512010
142
16317
T21
L
K
D
H
R
I
S
T
F
K
N
W
P
F
L
Rhesus Macaque
Macaca mulatta
XP_001108164
142
16287
T21
L
K
D
H
R
I
S
T
F
K
N
W
P
F
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O70201
140
16279
T21
L
K
N
Y
R
I
A
T
F
K
N
W
P
F
L
Rat
Rattus norvegicus
Q9JHY7
142
16674
T21
L
K
D
H
R
I
Y
T
F
K
N
W
P
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517041
145
16221
P24
W
P
L
Q
V
G
F
P
S
A
L
L
P
R
R
Chicken
Gallus gallus
NP_001012318
142
15926
T23
L
V
S
T
R
A
A
T
F
R
N
W
P
F
T
Frog
Xenopus laevis
Q50L39
157
18311
T34
K
L
A
S
R
L
R
T
F
S
N
W
P
F
T
Zebra Danio
Brachydanio rerio
NP_919378
142
16393
M37
C
V
C
T
P
E
N
M
A
K
A
G
F
I
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796206
147
17303
S29
F
E
A
N
R
L
D
S
F
K
D
W
P
F
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
97.8
N.A.
N.A.
82.3
82.3
N.A.
57.2
59.1
51.5
49.2
N.A.
N.A.
N.A.
N.A.
44.2
Protein Similarity:
100
99.3
98.5
N.A.
N.A.
91.5
90.8
N.A.
72.4
73.2
66.8
64
N.A.
N.A.
N.A.
N.A.
65.3
P-Site Identity:
100
100
100
N.A.
N.A.
80
93.3
N.A.
6.6
53.3
46.6
6.6
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
93.3
N.A.
6.6
66.6
53.3
13.3
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
0
10
20
0
10
10
10
0
0
0
0
% A
% Cys:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
40
0
0
0
10
0
0
0
10
0
0
0
0
% D
% Glu:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
10
0
80
0
0
0
10
80
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
40
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
50
0
0
0
0
0
0
0
10
0
% I
% Lys:
10
50
0
0
0
0
0
0
0
70
0
0
0
0
0
% K
% Leu:
60
10
10
0
0
20
0
0
0
0
10
10
0
0
60
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
0
10
0
0
0
70
0
0
0
0
% N
% Pro:
0
10
0
0
10
0
0
10
0
0
0
0
90
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
80
0
10
0
0
10
0
0
0
10
10
% R
% Ser:
0
0
10
10
0
0
30
10
10
10
0
0
0
0
0
% S
% Thr:
0
0
0
20
0
0
0
70
0
0
0
0
0
0
20
% T
% Val:
0
20
0
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
80
0
0
0
% W
% Tyr:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _