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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IPO8
All Species:
26.97
Human Site:
Y598
Identified Species:
49.44
UniProt:
O15397
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15397
NP_006381.2
1037
119938
Y598
K
V
L
Q
S
D
E
Y
E
E
V
E
D
K
T
Chimpanzee
Pan troglodytes
XP_528766
1037
119920
Y598
K
V
L
Q
S
D
E
Y
E
E
V
E
D
K
T
Rhesus Macaque
Macaca mulatta
XP_001082349
1037
119946
Y598
K
V
L
Q
S
D
E
Y
E
E
V
E
D
K
T
Dog
Lupus familis
XP_852181
1037
119835
Y598
K
V
L
Q
S
D
E
Y
E
E
I
E
D
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMY7
1010
117031
Y598
K
V
L
Q
S
D
E
Y
E
E
I
E
D
K
T
Rat
Rattus norvegicus
NP_001101015
1038
119470
D597
Q
V
I
Q
T
G
P
D
E
E
G
S
D
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507938
1038
119442
D597
Q
V
I
Q
T
G
P
D
E
E
G
G
D
D
K
Chicken
Gallus gallus
XP_416373
1171
133054
Y725
K
V
L
Q
S
E
E
Y
E
E
V
E
D
K
T
Frog
Xenopus laevis
NP_001079634
1038
119416
D597
Q
V
I
Q
T
G
P
D
E
E
G
S
D
D
K
Zebra Danio
Brachydanio rerio
NP_001037799
1015
117086
Y598
K
I
L
Q
S
E
E
Y
E
E
S
E
D
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524780
1049
119292
G599
Q
V
L
E
S
E
E
G
S
D
E
K
A
I
T
Honey Bee
Apis mellifera
XP_624116
1028
117714
G569
Q
V
L
E
T
D
E
G
S
D
E
K
A
I
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P46970
1048
119965
I637
S
F
T
N
V
D
S
I
P
D
E
S
D
K
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.7
96.6
N.A.
89.9
64.3
N.A.
64.8
77.2
63
71
N.A.
48.9
52.1
N.A.
N.A.
Protein Similarity:
100
99.9
99.7
98
N.A.
94.5
79.3
N.A.
79.3
82.8
78.1
84
N.A.
69.2
71.3
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
33.3
N.A.
33.3
93.3
33.3
80
N.A.
33.3
33.3
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
53.3
N.A.
53.3
100
53.3
93.3
N.A.
66.6
66.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
54
0
24
0
24
0
0
85
24
0
% D
% Glu:
0
0
0
16
0
24
70
0
77
77
24
54
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
24
0
16
0
0
24
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
24
0
0
0
0
8
0
0
16
0
0
16
0
% I
% Lys:
54
0
0
0
0
0
0
0
0
0
0
16
0
62
24
% K
% Leu:
0
0
70
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
24
0
8
0
0
0
0
0
0
% P
% Gln:
39
0
0
77
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
62
0
8
0
16
0
8
24
0
0
0
% S
% Thr:
0
0
8
0
31
0
0
0
0
0
0
0
0
0
70
% T
% Val:
0
85
0
0
8
0
0
0
0
0
31
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _