KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IPO8
All Species:
22.73
Human Site:
Y958
Identified Species:
41.67
UniProt:
O15397
Number Species:
12
Phosphosite Substitution
Charge Score:
0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15397
NP_006381.2
1037
119938
Y958
L
D
N
S
V
D
E
Y
Q
F
F
T
Q
A
L
Chimpanzee
Pan troglodytes
XP_528766
1037
119920
Y958
L
D
N
S
V
D
E
Y
Q
F
F
T
Q
A
L
Rhesus Macaque
Macaca mulatta
XP_001082349
1037
119946
Y958
L
D
N
S
V
D
E
Y
Q
F
F
T
Q
A
L
Dog
Lupus familis
XP_852181
1037
119835
Y958
L
D
N
S
V
D
E
Y
Q
F
F
T
Q
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMY7
1010
117031
Q914
E
E
T
S
V
S
A
Q
A
M
Q
S
Q
I
G
Rat
Rattus norvegicus
NP_001101015
1038
119470
Y959
E
D
N
P
V
D
E
Y
Q
I
F
K
A
I
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507938
1038
119442
Y959
E
D
N
P
V
D
E
Y
Q
I
F
K
A
I
F
Chicken
Gallus gallus
XP_416373
1171
133054
Y1092
L
E
N
G
V
D
E
Y
Q
F
F
T
Q
A
L
Frog
Xenopus laevis
NP_001079634
1038
119416
E958
D
E
D
T
P
I
D
E
Y
Q
I
F
K
A
I
Zebra Danio
Brachydanio rerio
NP_001037799
1015
117086
E936
D
D
D
E
D
D
D
E
Y
W
D
D
E
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524780
1049
119292
D966
S
F
T
T
P
I
D
D
E
E
N
E
S
A
I
Honey Bee
Apis mellifera
XP_624116
1028
117714
E949
S
D
D
M
N
Q
D
E
Y
V
V
F
K
E
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P46970
1048
119965
E960
D
D
D
E
N
D
D
E
G
D
L
T
E
K
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.7
96.6
N.A.
89.9
64.3
N.A.
64.8
77.2
63
71
N.A.
48.9
52.1
N.A.
N.A.
Protein Similarity:
100
99.9
99.7
98
N.A.
94.5
79.3
N.A.
79.3
82.8
78.1
84
N.A.
69.2
71.3
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
20
53.3
N.A.
53.3
86.6
6.6
20
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
33.3
53.3
N.A.
53.3
93.3
46.6
46.6
N.A.
33.3
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
8
0
0
0
16
54
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
70
31
0
8
70
39
8
0
8
8
8
0
0
0
% D
% Glu:
24
24
0
16
0
0
54
31
8
8
0
8
16
8
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
39
54
16
0
0
16
% F
% Gly:
0
0
0
8
0
0
0
0
8
0
0
0
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
16
0
0
0
16
8
0
0
24
16
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
16
16
8
0
% K
% Leu:
39
0
0
0
0
0
0
0
0
0
8
0
0
0
47
% L
% Met:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
54
0
16
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
16
16
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
8
54
8
8
0
47
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
16
0
0
39
0
8
0
0
0
0
0
8
8
0
0
% S
% Thr:
0
0
16
16
0
0
0
0
0
0
0
47
0
0
0
% T
% Val:
0
0
0
0
62
0
0
0
0
8
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
24
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _