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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STX7 All Species: 31.21
Human Site: S129 Identified Species: 57.22
UniProt: O15400 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15400 NP_003560.2 261 29816 S129 V R A S S R V S G S F P E D S
Chimpanzee Pan troglodytes XP_518745 261 29806 S129 V R A S S R V S G S F P E D S
Rhesus Macaque Macaca mulatta XP_001102703 261 29726 S129 V R A S S R V S G G F P E D S
Dog Lupus familis XP_849546 261 29722 S129 V R A S S R V S G G F P E D S
Cat Felis silvestris
Mouse Mus musculus O70439 261 29802 S129 V R A S S R V S G G F P E D S
Rat Rattus norvegicus O70257 261 29832 S129 V R A S S R V S G G F P E D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506421 262 29655 S129 V R A S S R V S G G F P E D S
Chicken Gallus gallus NP_001012961 258 29324 R125 A R V R A S S R I S G G A P E
Frog Xenopus laevis NP_001079671 259 29246 S127 V R A G S R V S G G F P D D N
Zebra Danio Brachydanio rerio XP_697581 267 30970 S135 V A R A R A G S R F Q V D E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396269 271 30684 A139 V R R A K A S A G I T P F G E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39233 279 31043 A150 E I P T S Y N A P E L D T E S
Baker's Yeast Sacchar. cerevisiae P32854 288 32988 M153 E S L E A S E M A N D A A L L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.6 92.7 N.A. 93.4 92.7 N.A. 89.6 79.6 66.2 53.5 N.A. N.A. 43.5 N.A. N.A.
Protein Similarity: 100 99.6 97.6 96.1 N.A. 96.1 96.5 N.A. 94.6 89.2 82.7 73 N.A. N.A. 66 N.A. N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 93.3 13.3 73.3 13.3 N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 93.3 20 86.6 33.3 N.A. N.A. 40 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.1 27.4 N.A.
Protein Similarity: N.A. N.A. N.A. 50.9 48.6 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 62 16 16 16 0 16 8 0 0 8 16 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 8 8 16 62 0 % D
% Glu: 16 0 0 8 0 0 8 0 0 8 0 0 54 16 16 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 62 0 8 0 0 % F
% Gly: 0 0 0 8 0 0 8 0 70 47 8 8 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 8 8 0 0 0 0 0 % I
% Lys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 8 0 0 0 0 0 0 0 8 0 0 8 16 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 8 % N
% Pro: 0 0 8 0 0 0 0 0 8 0 0 70 0 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 77 16 8 8 62 0 8 8 0 0 0 0 0 0 % R
% Ser: 0 8 0 54 70 16 16 70 0 24 0 0 0 0 62 % S
% Thr: 0 0 0 8 0 0 0 0 0 0 8 0 8 0 0 % T
% Val: 77 0 8 0 0 0 62 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _