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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STX7 All Species: 41.52
Human Site: Y230 Identified Species: 76.11
UniProt: O15400 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15400 NP_003560.2 261 29816 Y230 Q L S R A A D Y Q R K S R K T
Chimpanzee Pan troglodytes XP_518745 261 29806 Y230 Q L S R A A D Y Q R K S R K T
Rhesus Macaque Macaca mulatta XP_001102703 261 29726 Y230 Q L S R A A D Y Q R K S R K T
Dog Lupus familis XP_849546 261 29722 Y230 Q L S R A A E Y Q R K S R K T
Cat Felis silvestris
Mouse Mus musculus O70439 261 29802 Y230 Q L S R A A D Y Q R K S R K T
Rat Rattus norvegicus O70257 261 29832 Y230 Q L S R A A N Y Q R K S R K T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506421 262 29655 Y230 Q L S R A A E Y Q R K S R K T
Chicken Gallus gallus NP_001012961 258 29324 Y226 Q L A R A A N Y Q Q R S R K K
Frog Xenopus laevis NP_001079671 259 29246 Y228 Q L A T A A E Y Q R K S R R K
Zebra Danio Brachydanio rerio XP_697581 267 30970 Y236 Q L Q H A A Y Y Q R K S R K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396269 271 30684 Y240 H V R Q A S I Y Q N K L R K K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39233 279 31043 K250 V Q L R K A A K T Q R S N S S
Baker's Yeast Sacchar. cerevisiae P32854 288 32988 R259 D E L R K A M R Y Q K R T S R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.6 92.7 N.A. 93.4 92.7 N.A. 89.6 79.6 66.2 53.5 N.A. N.A. 43.5 N.A. N.A.
Protein Similarity: 100 99.6 97.6 96.1 N.A. 96.1 96.5 N.A. 94.6 89.2 82.7 73 N.A. N.A. 66 N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 100 93.3 N.A. 93.3 66.6 66.6 73.3 N.A. N.A. 40 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 86.6 73.3 N.A. N.A. 60 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.1 27.4 N.A.
Protein Similarity: N.A. N.A. N.A. 50.9 48.6 N.A.
P-Site Identity: N.A. N.A. N.A. 20 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 0 85 93 8 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 31 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 0 0 0 0 24 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 16 0 0 8 0 0 85 0 0 77 24 % K
% Leu: 0 77 16 0 0 0 0 0 0 0 0 8 0 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 16 0 0 8 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 77 8 8 8 0 0 0 0 85 24 0 0 0 0 0 % Q
% Arg: 0 0 8 77 0 0 0 8 0 70 16 8 85 8 16 % R
% Ser: 0 0 54 0 0 8 0 0 0 0 0 85 0 16 8 % S
% Thr: 0 0 0 8 0 0 0 0 8 0 0 0 8 0 54 % T
% Val: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 85 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _