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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STX7 All Species: 22.42
Human Site: Y69 Identified Species: 41.11
UniProt: O15400 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15400 NP_003560.2 261 29816 Y69 L A K E T D K Y I K E F G S L
Chimpanzee Pan troglodytes XP_518745 261 29806 Y69 L A K E T D K Y I K E F G S L
Rhesus Macaque Macaca mulatta XP_001102703 261 29726 Y69 L A K E T D K Y I K E F G S L
Dog Lupus familis XP_849546 261 29722 Y69 L A K E T D K Y I K E F G S L
Cat Felis silvestris
Mouse Mus musculus O70439 261 29802 Y69 L A K E T D K Y I K E F G S L
Rat Rattus norvegicus O70257 261 29832 Y69 L A K E T D K Y I K E F G F L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506421 262 29655 L69 L A K E T D K L I K E F G S L
Chicken Gallus gallus NP_001012961 258 29324 I69 A K E T D K Y I K E F G S L P
Frog Xenopus laevis NP_001079671 259 29246 L69 A K D T E R C L K D Y A S L P
Zebra Danio Brachydanio rerio XP_697581 267 30970 H76 L A K E T N R H L K D L G T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396269 271 30684 H77 L A K D T S V H L R D L A I L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39233 279 31043 K87 L V K N T S A K L K E A S E A
Baker's Yeast Sacchar. cerevisiae P32854 288 32988 G84 A K I E E I G G L I K K V N T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.6 92.7 N.A. 93.4 92.7 N.A. 89.6 79.6 66.2 53.5 N.A. N.A. 43.5 N.A. N.A.
Protein Similarity: 100 99.6 97.6 96.1 N.A. 96.1 96.5 N.A. 94.6 89.2 82.7 73 N.A. N.A. 66 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. 93.3 0 0 53.3 N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 93.3 13.3 0 93.3 N.A. N.A. 66.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.1 27.4 N.A.
Protein Similarity: N.A. N.A. N.A. 50.9 48.6 N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 70 0 0 0 0 8 0 0 0 0 16 8 0 8 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 8 8 54 0 0 0 8 16 0 0 0 0 % D
% Glu: 0 0 8 70 16 0 0 0 0 8 62 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 54 0 8 0 % F
% Gly: 0 0 0 0 0 0 8 8 0 0 0 8 62 0 0 % G
% His: 0 0 0 0 0 0 0 16 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 8 0 8 54 8 0 0 0 8 0 % I
% Lys: 0 24 77 0 0 8 54 8 16 70 8 8 0 0 0 % K
% Leu: 77 0 0 0 0 0 0 16 31 0 0 16 0 16 70 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 8 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 8 8 0 0 8 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 16 0 0 0 0 0 0 24 47 0 % S
% Thr: 0 0 0 16 77 0 0 0 0 0 0 0 0 8 8 % T
% Val: 0 8 0 0 0 0 8 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 47 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _